Oxidative stress and antioxidant defense systems status in diabetic rats feeding some selected plant partexctract
Other Title(s)
الإجهاد التأكسدى و مضادات الأكسدة للفئران المصابة بالسكري و التي تم تغذيتها على بعض مستخلصات الأجزاء النياتية
Joint Authors
al-Wasif, Safa Ali
Salim, Najla Fathi
Arif, Zaynab Ahmad
al-Zughi, Muhammad Sayyid
Source
Faculty of Specific Education Journal
Issue
Vol. 2021, Issue 13 (31 Jan. 2021), pp.611-639, 29 p.
Publisher
Port Said University Faculty of Specified Education
Publication Date
2021-01-31
Country of Publication
Egypt
No. of Pages
29
Main Subjects
Topics
Abstract EN
Oxidative stress plays a pathological role in the development of various diseases including diabetes.
Systemic oxidative stress results from an imbalance between oxidants derivatives production and antioxidants defenses.
The present study aims to investigate the oxidative stress and antioxidant defense system status in diabetic rats feeding some selected plant parts such okra fruits water extract (OFWE), white mulberry leaves water extract (MLWE), celery leaves water extract (CLWE) and their Mixture.
Treatment of animals with alloxancaused a significant increased (p≤0.05) in serum glucose concentration by the ratio 136.51% compared to positive animals (negative control group).
Supplementation of the rat diets with 2% w/w by OFWE, MLWE, CLWE and their mixture decreased this elevation value compared to normal controls and recorded 57.35, 38.69, 52.27 and 35.48%, respectively.
Also, consumption of OFWE, MLWE, CLWE and their mixture induced significant improvements on serum glutathione fractions concentration through increasing the reduced glutathione (GSH) and oxidized glutathione compared to positive controls by the ratio of -15.31; -11.22, -14.29 and -7.14%; and -15.31, -11.22, -14.29 and -7.14%, respectively.
The opposite direction was observed with the biological oxidants includingthiobarbituric acid reactive substances (TBARS) and nitric oxides (NO2 and NO3).In conclusion,the present data support the benefits of dietary modification, including bioactive compounds and antioxidant vitamins supplementation, in alleviating oxidative stress associated diabetes.
American Psychological Association (APA)
Arif, Zaynab Ahmad& al-Zughi, Muhammad Sayyid& al-Wasif, Safa Ali& Salim, Najla Fathi. 2021. Oxidative stress and antioxidant defense systems status in diabetic rats feeding some selected plant partexctract. Faculty of Specific Education Journal،Vol. 2021, no. 13, pp.611-639.
https://search.emarefa.net/detail/BIM-1030481
Modern Language Association (MLA)
Arif, Zaynab Ahmad…[et al.]. Oxidative stress and antioxidant defense systems status in diabetic rats feeding some selected plant partexctract. Faculty of Specific Education Journal No. 13 (Jan. 2021), pp.611-639.
https://search.emarefa.net/detail/BIM-1030481
American Medical Association (AMA)
Arif, Zaynab Ahmad& al-Zughi, Muhammad Sayyid& al-Wasif, Safa Ali& Salim, Najla Fathi. Oxidative stress and antioxidant defense systems status in diabetic rats feeding some selected plant partexctract. Faculty of Specific Education Journal. 2021. Vol. 2021, no. 13, pp.611-639.
https://search.emarefa.net/detail/BIM-1030481
Data Type
Journal Articles
Language
English
Notes
-
Record ID
BIM-1030481