Exercise Improves Immune Function, Antidepressive Response, and Sleep Quality in Patients with Chronic Primary Insomnia
Joint Authors
de Mello, Marco Tulio
dos Santos, Ronaldo Vagner Thomathieli
Passos, Giselle Soares
Poyares, Dalva
Santana, Marcos Gonçalves
Teixeira, Alexandre Abílio de Souza
Youngstedt, Shawn D.
Tufik, Sergio
Lira, Fabio Santos
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The aim of this study was to evaluate the effects of moderate aerobic exercise training on sleep, depression, cortisol, and markers of immune function in patients with chronic primary insomnia.
Twenty-one sedentary participants (16 women aged 44.7 ± 9 years) with chronic primary insomnia completed a 4-month intervention of moderate aerobic exercise.
Compared with baseline, polysomnographic data showed improvements following exercise training.
Also observed were reductions in depression symptoms and plasma cortisol.
Immunologic assays revealed a significant increase in plasma apolipoprotein A (140.9 ± 22 to 151.2 ± 22 mg/dL) and decreases in CD4 (915.6 ± 361 to 789.6 ± 310 mm3) and CD8 (532.4 ± 259 to 435.7 ± 204 mm3).
Decreases in cortisol were significantly correlated with increases in total sleep time (r=-0.51) and REM sleep (r=-0.52).
In summary, long-term moderate aerobic exercise training improved sleep, reduced depression and cortisol, and promoted significant changes in immunologic variables.
American Psychological Association (APA)
Passos, Giselle Soares& Poyares, Dalva& Santana, Marcos Gonçalves& Teixeira, Alexandre Abílio de Souza& Lira, Fabio Santos& Youngstedt, Shawn D.…[et al.]. 2014. Exercise Improves Immune Function, Antidepressive Response, and Sleep Quality in Patients with Chronic Primary Insomnia. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034480
Modern Language Association (MLA)
Passos, Giselle Soares…[et al.]. Exercise Improves Immune Function, Antidepressive Response, and Sleep Quality in Patients with Chronic Primary Insomnia. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1034480
American Medical Association (AMA)
Passos, Giselle Soares& Poyares, Dalva& Santana, Marcos Gonçalves& Teixeira, Alexandre Abílio de Souza& Lira, Fabio Santos& Youngstedt, Shawn D.…[et al.]. Exercise Improves Immune Function, Antidepressive Response, and Sleep Quality in Patients with Chronic Primary Insomnia. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034480
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034480