Effects of Dietary Supplementation with Agaricus sylvaticus Schaeffer on Glycemia and Cholesterol after Streptozotocin-Induced Diabetes in Rats
Joint Authors
França, Cristiane M.
Mascaro, Marcelo Betti
Esquerdo, Kamilla F.
Lara, Marx A. N.
Wadt, Nilsa S. Y.
Bach, Erna E.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
This study evaluated the effect of the Agaricus sylvaticus (sun mushroom) on biochemical tests of the plasma and on the morphology of the pancreas in an experimental model of type I diabetes mellitus (DM1) induced by streptozotocin.
One gram of dry A.
sylvaticus was homogenized and mixed with the chow.
Male Wistar rats were allocated as follows: normoglycemic control that received commercial chow; normoglycemic control group that received chow with A.
sylvaticus; diabetic group that received commercial chow; and diabetic group that received chow with A.
sylvaticus.
Weight, food, and water consumption were measured every two days.
Blood glucose levels were measured twice a week.
After 30 days, the animals were euthanized and blood was collected for the analysis of cholesterol, HDL, triglycerides, blood sugar, glutamic-pyruvic transaminase (GPT), alkaline phosphatase, iron, transferrin, and urea.
The pancreas was processed for microscopic analysis.
A.
sylvaticus modulated the levels of cholesterol, HDL, triglycerides, blood sugar, GPT, alkaline phosphatase, iron, transferrin, and urea to levels similar to those found in the controls and led to compensatory hyperplasia of the islets of Langerhans.
A.
sylvaticus is potentially beneficial in the control of type 1 diabetes, and it may also prevent pancreas damage.
American Psychological Association (APA)
Mascaro, Marcelo Betti& França, Cristiane M.& Esquerdo, Kamilla F.& Lara, Marx A. N.& Wadt, Nilsa S. Y.& Bach, Erna E.. 2014. Effects of Dietary Supplementation with Agaricus sylvaticus Schaeffer on Glycemia and Cholesterol after Streptozotocin-Induced Diabetes in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035094
Modern Language Association (MLA)
Mascaro, Marcelo Betti…[et al.]. Effects of Dietary Supplementation with Agaricus sylvaticus Schaeffer on Glycemia and Cholesterol after Streptozotocin-Induced Diabetes in Rats. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1035094
American Medical Association (AMA)
Mascaro, Marcelo Betti& França, Cristiane M.& Esquerdo, Kamilla F.& Lara, Marx A. N.& Wadt, Nilsa S. Y.& Bach, Erna E.. Effects of Dietary Supplementation with Agaricus sylvaticus Schaeffer on Glycemia and Cholesterol after Streptozotocin-Induced Diabetes in Rats. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035094
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1035094