Antimetastatic and Anti-Inflammatory Potentials of Essential Oil from Edible Ocimum sanctum Leaves
Joint Authors
Manaharan, Thamilvaani
Thirugnanasampandan, Ramaraj
Jayakumar, Rajarajeswaran
Ramya, Gunasekar
Ramnath, Gogul
Kanthimathi, M. S.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Antimetastatic and anti-inflammatory activities of Ocimum sanctum essential oil (OSEO) have been assessed in this study.
OSEO at the concentration of 250 μg/mL and above showed a significant (P*<0.05) decrease in the number of migrated cancer cells.
In addition, OSEO at concentration of 250 μg/mL and above suppressed MMP-9 activity in lipopolysaccharide (LPS) induced inflammatory cells.
A dose-dependent downregulation of MMP-9 expression was observed with the treatment of OSEO compared to the control.
Our findings indicate that OSEO has both antimetastatic and anti-inflammatory potentials, advocating further investigation for clinical applications in the treatment of inflammation associated cancer.
American Psychological Association (APA)
Manaharan, Thamilvaani& Thirugnanasampandan, Ramaraj& Jayakumar, Rajarajeswaran& Ramya, Gunasekar& Ramnath, Gogul& Kanthimathi, M. S.. 2014. Antimetastatic and Anti-Inflammatory Potentials of Essential Oil from Edible Ocimum sanctum Leaves. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1048847
Modern Language Association (MLA)
Manaharan, Thamilvaani…[et al.]. Antimetastatic and Anti-Inflammatory Potentials of Essential Oil from Edible Ocimum sanctum Leaves. The Scientific World Journal No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1048847
American Medical Association (AMA)
Manaharan, Thamilvaani& Thirugnanasampandan, Ramaraj& Jayakumar, Rajarajeswaran& Ramya, Gunasekar& Ramnath, Gogul& Kanthimathi, M. S.. Antimetastatic and Anti-Inflammatory Potentials of Essential Oil from Edible Ocimum sanctum Leaves. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1048847
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048847
