Numerical Investigation of the Effect of Stenosis Geometry on the Coronary Diagnostic Parameters
Joint Authors
Badarudin, A.
Kamangar, Sarfaraz
Kalimuthu, Govindaraju
Anjum Badruddin, Irfan
Salman Ahmed, N. J.
Khan, T. M. Yunus
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
The present study deals with the functional severity of a coronary artery stenosis assessed by the fractional flow reserve (FFR).
The effects of different geometrical shapes of lesion on the diagnostic parameters are unknown.
In this study, 3D computational simulation of blood flow in three different geometrical shapes of stenosis (triangular, elliptical, and trapezium) is considered in steady and transient conditions for 70% (moderate), 80% (intermediate), and 90% (severe) area stenosis (AS).
For a given percentage AS, the variation of diagnostic parameters which are derived from pressure drop across the stenosis was found in three different geometrical shapes of stenosis and it was observed that FFR is higher in triangular shape and lower in trapezium shape.
The pressure drop coefficient (CDP) was higher in trapezium shape and lower in triangular model whereas the LFC shows opposite trend.
From the clinical perspective, the relationship between percentage AS and FFR is linear and inversely related in all the three models.
A cut-off value of 0.75 for FFR was observed at 76.5% AS in trapezium model, 79.5% in elliptical model, and 82.7% AS for the triangular shaped model.
The misinterpretation of the functional severity of the stenosis is in the region of 76.5%-82.7 % AS from different shapes of stenosis models.
American Psychological Association (APA)
Kamangar, Sarfaraz& Kalimuthu, Govindaraju& Anjum Badruddin, Irfan& Badarudin, A.& Salman Ahmed, N. J.& Khan, T. M. Yunus. 2014. Numerical Investigation of the Effect of Stenosis Geometry on the Coronary Diagnostic Parameters. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1049307
Modern Language Association (MLA)
Kamangar, Sarfaraz…[et al.]. Numerical Investigation of the Effect of Stenosis Geometry on the Coronary Diagnostic Parameters. The Scientific World Journal No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1049307
American Medical Association (AMA)
Kamangar, Sarfaraz& Kalimuthu, Govindaraju& Anjum Badruddin, Irfan& Badarudin, A.& Salman Ahmed, N. J.& Khan, T. M. Yunus. Numerical Investigation of the Effect of Stenosis Geometry on the Coronary Diagnostic Parameters. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1049307
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1049307