![](/images/graphics-bg.png)
Quantification of Osseointegration of Plasma-Polymer Coated Titanium Alloyed Implants by means of Microcomputed Tomography versus Histomorphometry
Joint Authors
Gabler, Carolin
Bieck, Richard
Göhler, Rebecca
Haenle, Maximilian
Meichsner, Jürgen
Testrich, Holger
Nowottnick, Mathias
Frerich, Bernhard
Finke, Birgit
Lindner, Tobias
Bader, Rainer
Zietz, Carmen
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A common method to derive both qualitative and quantitative data to evaluate osseointegration of implants is histomorphometry.
The present study describes a new image reconstruction algorithm comparing the results of bone-to-implant contact (BIC) evaluated by means of µCT with histomorphometry data.
Custom-made conical titanium alloyed (Ti6Al4V) implants were inserted in the distal tibial bone of female Sprague-Dawley rats.
Different surface configurations were examined: Ti6Al4V implants with plasma-polymerized allylamine (PPAAm) coating and plasma-polymerized ethylenediamine (PPEDA) coating as well as implants without surface coating.
After six weeks postoperatively, tibiae were explanted and BIC was determined by µCT (3D) and afterwards by histomorphometry (2D).
In comparison to uncoated Ti6Al4V implants demonstrating low BIC of 32.4% (histomorphometry) and 51.3% (µCT), PPAAm and PPEDA coated implants showed a nonsignificant increase in BIC (histomorphometry: 45.7% and 53.5% and µCT: 51.8% and 62.0%, resp.).
Mean BIC calculated by µCT was higher for all surface configurations compared to BIC detected by histomorphometry.
Overall, a high correlation coefficient of 0.70 ( p < 0.002 ) was found between 3D and 2D quantification of BIC.
The μCT analysis seems to be suitable as a nondestructive and accurate 3D imaging method for the evaluation of the bone-implant interface.
American Psychological Association (APA)
Gabler, Carolin& Zietz, Carmen& Bieck, Richard& Göhler, Rebecca& Lindner, Tobias& Haenle, Maximilian…[et al.]. 2015. Quantification of Osseointegration of Plasma-Polymer Coated Titanium Alloyed Implants by means of Microcomputed Tomography versus Histomorphometry. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054217
Modern Language Association (MLA)
Gabler, Carolin…[et al.]. Quantification of Osseointegration of Plasma-Polymer Coated Titanium Alloyed Implants by means of Microcomputed Tomography versus Histomorphometry. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1054217
American Medical Association (AMA)
Gabler, Carolin& Zietz, Carmen& Bieck, Richard& Göhler, Rebecca& Lindner, Tobias& Haenle, Maximilian…[et al.]. Quantification of Osseointegration of Plasma-Polymer Coated Titanium Alloyed Implants by means of Microcomputed Tomography versus Histomorphometry. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1054217
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054217