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Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties
Joint Authors
Marín, Laura
Miguélez, Elisa M.
Villar, Claudio J.
Lombó, Felipe
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-23
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Polyphenolic compounds are plant nutraceuticals showing a huge structural diversity, including chlorogenic acids, hydrolyzable tannins, and flavonoids (flavonols, flavanones, flavan-3-ols, anthocyanidins, isoflavones, and flavones).
Most of them occur as glycosylated derivatives in plants and foods.
In order to become bioactive at human body, these polyphenols must undergo diverse intestinal transformations, due to the action of digestive enzymes, but also by the action of microbiota metabolism.
After elimination of sugar tailoring (generating the corresponding aglycons) and diverse hydroxyl moieties, as well as further backbone reorganizations, the final absorbed compounds enter the portal vein circulation towards liver (where other enzymatic transformations take place) and from there to other organs, including behind the digestive tract or via blood towards urine excretion.
During this transit along diverse tissues and organs, they are able to carry out strong antiviral, antibacterial, and antiparasitic activities.
This paper revises and discusses these antimicrobial activities of dietary polyphenols and their relevance for human health, shedding light on the importance of polyphenols structure recognition by specific enzymes produced by intestinal microbial taxa.
American Psychological Association (APA)
Marín, Laura& Miguélez, Elisa M.& Villar, Claudio J.& Lombó, Felipe. 2015. Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties. BioMed Research International،Vol. 2015, no. 2015, pp.1-18.
https://search.emarefa.net/detail/BIM-1057182
Modern Language Association (MLA)
Marín, Laura…[et al.]. Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties. BioMed Research International No. 2015 (2015), pp.1-18.
https://search.emarefa.net/detail/BIM-1057182
American Medical Association (AMA)
Marín, Laura& Miguélez, Elisa M.& Villar, Claudio J.& Lombó, Felipe. Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-18.
https://search.emarefa.net/detail/BIM-1057182
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057182