Circulating Soluble Neuropilin-1 in Patients with Early Cervical Cancer and Cervical Intraepithelial Neoplasia Can Be Used as a Valuable Diagnostic Biomarker
Joint Authors
Yang, Shouhua
Cheng, Henghui
Huang, Zaiju
Wang, Xiaoling
Wan, Yinglu
Cai, Jing
Wang, Zehua
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To investigate soluble neuropilin-1 (sNRP-1) in circulating and NRP-1 protein in cervical tissues from patients with cervical cancer or cervical intraepithelial neoplasia (CIN).
Methods.
sNRP-1 was measured in 64 preoperative patients and 20 controls.
NRP-1 protein in cervical tissue was detected in 56 patients and 20 controls.
Results.
Both sNRP-1 and NRP-1 proteins were correlated with stage.
sNRP-1 presented a high diagnostic ability of cervical cancer and CIN, with a sensitivity of 70.97% and a specificity of 73.68%.
Conclusions.
sNRP-1 in circulating can serve as a possible valuable diagnostic biomarker for cervical cancer and CIN.
American Psychological Association (APA)
Yang, Shouhua& Cheng, Henghui& Huang, Zaiju& Wang, Xiaoling& Wan, Yinglu& Cai, Jing…[et al.]. 2015. Circulating Soluble Neuropilin-1 in Patients with Early Cervical Cancer and Cervical Intraepithelial Neoplasia Can Be Used as a Valuable Diagnostic Biomarker. Disease Markers،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060963
Modern Language Association (MLA)
Yang, Shouhua…[et al.]. Circulating Soluble Neuropilin-1 in Patients with Early Cervical Cancer and Cervical Intraepithelial Neoplasia Can Be Used as a Valuable Diagnostic Biomarker. Disease Markers No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1060963
American Medical Association (AMA)
Yang, Shouhua& Cheng, Henghui& Huang, Zaiju& Wang, Xiaoling& Wan, Yinglu& Cai, Jing…[et al.]. Circulating Soluble Neuropilin-1 in Patients with Early Cervical Cancer and Cervical Intraepithelial Neoplasia Can Be Used as a Valuable Diagnostic Biomarker. Disease Markers. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1060963
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1060963
