Psychological Therapies in Patients with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Joint Authors
Sood, Amit
Altayar, Osama
Sharma, Varun
Prokop, Larry J.
Murad, Mohammad Hassan
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-31
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Background.
Irritable bowel syndrome (IBS) is a poorly understood disease with few effective treatments.
Psychosocial factors are believed to contribute to the pathogenesis of IBS.
Objective.
To evaluate the evidence for psychological therapies in IBS treatment.
Methods.
We searched six medical databases through February 6, 2014, for randomized controlled trials (RCTs) of psychological therapies for the treatment of IBS.
Two independent reviewers identified the RCTs, extracted the data, and assessed trial quality.
We used the random-effect model to pool standardized mean difference (SMD) and 95% confidence interval (CI) across trials.
Results.
15 RCTs that mostly evaluated cognitive behavioral therapy were included.
Psychological therapies were associated with improvement in IBS symptoms severity scales (SMD −0.618; 95% CI: −0.853 to −0.383), IBS-Quality of Life (SMD 0.604; 95% CI: 0.440 to 0.768), and abdominal pain (SMD −0.282; 95% CI: −0.562 to −0.001).
No statistically significant effect was observed on diarrhea or constipation.
Limitations.
The trials were at increased risk of bias and the overall sample size was small leading to imprecision.
Conclusion.
Psychological therapies may improve the quality of life and symptom severity in IBS.
The effect size noted is moderate to large and is clinically meaningful.
American Psychological Association (APA)
Altayar, Osama& Sharma, Varun& Prokop, Larry J.& Sood, Amit& Murad, Mohammad Hassan. 2015. Psychological Therapies in Patients with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-19.
https://search.emarefa.net/detail/BIM-1064035
Modern Language Association (MLA)
Altayar, Osama…[et al.]. Psychological Therapies in Patients with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Gastroenterology Research and Practice No. 2015 (2015), pp.1-19.
https://search.emarefa.net/detail/BIM-1064035
American Medical Association (AMA)
Altayar, Osama& Sharma, Varun& Prokop, Larry J.& Sood, Amit& Murad, Mohammad Hassan. Psychological Therapies in Patients with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-19.
https://search.emarefa.net/detail/BIM-1064035
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064035