Inhibitory Effects of 4-(4-Methylbenzamino)benzoate on Adipocyte Differentiation
Joint Authors
Kim, Sanghee
Yoon, Bo-ra
Choi, Inwook
Choi, Sang Yoon
Hwang, Jin-Taek
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The potent suppression of adipocyte differentiation by 4-(4-methylbenzamino)benzoate was discovered during the search for new antiobesity compounds.
4-(4-methylbenzamino)benzoate was observed to suppress adipocyte differentiation in 3T3-L1 cells by 96.8% at 50 μM without cytotoxicity.
In addition, 4-(4-methylbenzamino)benzoate reduced the cellular expression of fatty acid synthase in a concentration-dependent manner, as well as suppressing PPAR-gamma activity, which controls fatty acid storage and glucose metabolism.
Based on these results, 4-(4-methylbenzamino)benzoate shows potential as an antiobesity material.
American Psychological Association (APA)
Hwang, Jin-Taek& Kim, Sanghee& Yoon, Bo-ra& Choi, Inwook& Choi, Sang Yoon. 2015. Inhibitory Effects of 4-(4-Methylbenzamino)benzoate on Adipocyte Differentiation. Journal of Chemistry،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1067331
Modern Language Association (MLA)
Hwang, Jin-Taek…[et al.]. Inhibitory Effects of 4-(4-Methylbenzamino)benzoate on Adipocyte Differentiation. Journal of Chemistry No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1067331
American Medical Association (AMA)
Hwang, Jin-Taek& Kim, Sanghee& Yoon, Bo-ra& Choi, Inwook& Choi, Sang Yoon. Inhibitory Effects of 4-(4-Methylbenzamino)benzoate on Adipocyte Differentiation. Journal of Chemistry. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1067331
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1067331
