The role of natural of antisensetranscription HAGLR,LCMT1AS, NAV2AS5,TSIX in breast cancer
Other Title(s)
دور النسخ الطبيعيه غير الحسيه للجينات HAGLR، LCMT1AS، NAV2AS5 ، TSIX في سرطان الثدي
Joint Authors
Said, Chiman Hamid
Balcı, Sibel Oguzkan
Saadat, Khandakar A. S. M.
Qurayshi, Ishan Rafat
Amin, Yasin Karim
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 27, Issue 2 (30 Apr. 2019), pp.380-387, 8 p.
Publisher
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
Backgraound: lncRNAs (longnon-codingRNAs), has avarious important molecular and cellular functions and natural antisense transcripts (NATs), complementary to protein-coding or non-coding.
RNA sequences are important regulators of gene expression drew a great attention recent years to uncover their importance for diagnostic, prognostic and therapeutic purposes; and their dysfunctions leads to diseases including cancer.
Aims:The aim of this study was to investigate important roles of lncNATs TSIX, HAGLR, LMCT1AS and NAV2AS5 genes in several tumorigenic processes in breast cancer.
Materials andMethods: In this study we used ATCC normal cell lines (CRL4010,CRL8798) and cancer cell lines (MCF7,MDA-MB231,CRL2329) that subjected.
To examine through RNA isolation,cDNAconversion, semiquantitative (by agarose gel and ImageJ program) and quantitative RT-PCR for gene expression analyses.
Results:Our results have been shown that TSIX, HAGLR, LMCT1AS and NAV2AS5 genes have differential expression pattern in both normal and breast cancer cell lines.
Conclution: from the data of our results we concluded that these genes have important role in biological procesess of breast cancer in addition their impotnace in treatment and therapeutic purpus.
American Psychological Association (APA)
Balcı, Sibel Oguzkan& Saadat, Khandakar A. S. M.& Qurayshi, Ishan Rafat& Amin, Yasin Karim& Said, Chiman Hamid. 2019. The role of natural of antisensetranscription HAGLR,LCMT1AS, NAV2AS5,TSIX in breast cancer. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 27, no. 2, pp.380-387.
https://search.emarefa.net/detail/BIM-1091190
Modern Language Association (MLA)
Balcı, Sibel Oguzkan…[et al.]. The role of natural of antisensetranscription HAGLR,LCMT1AS, NAV2AS5,TSIX in breast cancer. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 27, no. 2 (2019), pp.380-387.
https://search.emarefa.net/detail/BIM-1091190
American Medical Association (AMA)
Balcı, Sibel Oguzkan& Saadat, Khandakar A. S. M.& Qurayshi, Ishan Rafat& Amin, Yasin Karim& Said, Chiman Hamid. The role of natural of antisensetranscription HAGLR,LCMT1AS, NAV2AS5,TSIX in breast cancer. Journal of Babylon University : Journal of Applied and Pure Sciences. 2019. Vol. 27, no. 2, pp.380-387.
https://search.emarefa.net/detail/BIM-1091190
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 386-387
Record ID
BIM-1091190