Acute Oral Mammalian Toxicity and Effect of Solvents on Efficacy of Maerua edulis (Gilg. & Ben.) De Wolf against Rhipicephalus (Boophilus) decoloratus Koch, 1844 (Acarina: Ixodidae), Tick Larvae
Joint Authors
Nyahangare, Emmanuel T.
Mvumi, Brighton M.
Maramba, Tatenda
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Efficacy and toxicity of aqueous and organic solvents extracts of Maerua edulis against ticks and mice, respectively, were determined.
Ground leaves were extracted separately using cold water, cold water plus surfactant (1% v/v liquid soap), hot water plus surfactant, hexane, or methanol to make 25% w/v stock solutions from which serial dilutions of 5, 10, 20, and 25% were made.
For each concentration, 20 Rhipicephalus decoloratus tick larvae were put in filter papers impregnated with extracts and incubated for 48 h at 27°C and 85–90% RH for mortality observation after 24 h and 48 h.
In the toxicity experiment, hot water plus surfactant treatments of 5, 10, 20, and 25% (w/v) M.
edulis were administered in suspension per os to sexually mature Balb/C mice and observed for clinical signs and mortality for 72 h.
Larvae mortality was highest (>98%) in methanol-extracted M.
edulis treatments (20 and 25%), which was not different from the amitraz-based control (Tickbuster®).
Mortality was also higher in the hot water than in cold water plus surfactant treatments ( P < 0.05 ).
No postadministration adverse health effects were observed in the mice.
These results suggest that M.
edulis is an effective tick remedy best extracted using methanol or hot water plus surfactant.
American Psychological Association (APA)
Nyahangare, Emmanuel T.& Mvumi, Brighton M.& Maramba, Tatenda. 2016. Acute Oral Mammalian Toxicity and Effect of Solvents on Efficacy of Maerua edulis (Gilg. & Ben.) De Wolf against Rhipicephalus (Boophilus) decoloratus Koch, 1844 (Acarina: Ixodidae), Tick Larvae. BioMed Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098681
Modern Language Association (MLA)
Nyahangare, Emmanuel T.…[et al.]. Acute Oral Mammalian Toxicity and Effect of Solvents on Efficacy of Maerua edulis (Gilg. & Ben.) De Wolf against Rhipicephalus (Boophilus) decoloratus Koch, 1844 (Acarina: Ixodidae), Tick Larvae. BioMed Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1098681
American Medical Association (AMA)
Nyahangare, Emmanuel T.& Mvumi, Brighton M.& Maramba, Tatenda. Acute Oral Mammalian Toxicity and Effect of Solvents on Efficacy of Maerua edulis (Gilg. & Ben.) De Wolf against Rhipicephalus (Boophilus) decoloratus Koch, 1844 (Acarina: Ixodidae), Tick Larvae. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1098681
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1098681