Select and Cluster: A Method for Finding Functional Networks of Clustered Voxels in fMRI
Joint Authors
DonGiovanni, Danilo
Vaina, Lucia Maria
Source
Computational Intelligence and Neuroscience
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-05
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Extracting functional connectivity patterns among cortical regions in fMRI datasets is a challenge stimulating the development of effective data-driven or model based techniques.
Here, we present a novel data-driven method for the extraction of significantly connected functional ROIs directly from the preprocessed fMRI data without relying on a priori knowledge of the expected activations.
This method finds spatially compact groups of voxels which show a homogeneous pattern of significant connectivity with other regions in the brain.
The method, called Select and Cluster (S&C), consists of two steps: first, a dimensionality reduction step based on a blind multiresolution pairwise correlation by which the subset of all cortical voxels with significant mutual correlation is selected and the second step in which the selected voxels are grouped into spatially compact and functionally homogeneous ROIs by means of a Support Vector Clustering (SVC) algorithm.
The S&C method is described in detail.
Its performance assessed on simulated and experimental fMRI data is compared to other methods commonly used in functional connectivity analyses, such as Independent Component Analysis (ICA) or clustering.
S&C method simplifies the extraction of functional networks in fMRI by identifying automatically spatially compact groups of voxels (ROIs) involved in whole brain scale activation networks.
American Psychological Association (APA)
DonGiovanni, Danilo& Vaina, Lucia Maria. 2016. Select and Cluster: A Method for Finding Functional Networks of Clustered Voxels in fMRI. Computational Intelligence and Neuroscience،Vol. 2016, no. 2016, pp.1-19.
https://search.emarefa.net/detail/BIM-1099686
Modern Language Association (MLA)
DonGiovanni, Danilo& Vaina, Lucia Maria. Select and Cluster: A Method for Finding Functional Networks of Clustered Voxels in fMRI. Computational Intelligence and Neuroscience Vol. 2016, no. 2016 (2015), pp.1-19.
https://search.emarefa.net/detail/BIM-1099686
American Medical Association (AMA)
DonGiovanni, Danilo& Vaina, Lucia Maria. Select and Cluster: A Method for Finding Functional Networks of Clustered Voxels in fMRI. Computational Intelligence and Neuroscience. 2016. Vol. 2016, no. 2016, pp.1-19.
https://search.emarefa.net/detail/BIM-1099686
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1099686