![](/images/graphics-bg.png)
Takotsubo Cardiomyopathy and Catatonia in the Setting of Benzodiazepine Withdrawal
Joint Authors
Peng, Teng J.
Patchett, Nicholas D.
Bernard, Sheilah A.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-28
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We report two serious and unusual complications of benzodiazepine withdrawal in a single patient: takotsubo cardiomyopathy and catatonia.
This 61-year-old female patient was brought to the emergency department with lethargy and within hours had declined into a state of catatonia.
Although there was never a complaint of chest pain, ECG showed deep anterior T-wave inversions and cardiac enzymes were elevated.
An echocardiogram was consistent with takotsubo cardiomyopathy.
She later received 1 mg of midazolam and within minutes had resolution of catatonic symptoms.
Careful history revealed that she had omitted her daily dose of lorazepam for 3 days prior to admission.
To our knowledge, the case presented herein is the first report of simultaneous catatonia and takotsubo cardiomyopathy in the setting of benzodiazepine withdrawal.
The pathogenesis of both conditions is poorly understood but may be indirectly related to the sudden decrease in γ-aminobutyric acid (GABA) signaling during benzodiazepine withdrawal.
American Psychological Association (APA)
Peng, Teng J.& Patchett, Nicholas D.& Bernard, Sheilah A.. 2016. Takotsubo Cardiomyopathy and Catatonia in the Setting of Benzodiazepine Withdrawal. Case Reports in Cardiology،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100389
Modern Language Association (MLA)
Peng, Teng J.…[et al.]. Takotsubo Cardiomyopathy and Catatonia in the Setting of Benzodiazepine Withdrawal. Case Reports in Cardiology No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100389
American Medical Association (AMA)
Peng, Teng J.& Patchett, Nicholas D.& Bernard, Sheilah A.. Takotsubo Cardiomyopathy and Catatonia in the Setting of Benzodiazepine Withdrawal. Case Reports in Cardiology. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100389
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1100389