A Confirmatory Method Based on HPLC-MSMS for the Detection and Quantification of Residue of Tetracyclines in Nonmedicated Feed
Joint Authors
Cepeda, Alberto
Gavilán, Rosa E.
Nebot, Carolina
Veiga-Gómez, Maria
Roca-Saavedra, Paula
Vazquez Belda, Beatriz
Franco, Carlos M.
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The Commission Regulation 574/2011/EC set up maximum levels of coccidiostats and histomonostats in nonmedicated feed as a consequence of carry-over during manufacturing.
Carry-over takes place from medicated to nonmedicated feed during feed production.
Similar contamination could also occur for other pharmaceuticals such as tetracyclines, a group of antibiotics commonly employed in food production animal.
The objective of this work is to present a simple and fast method for the simultaneous detection of four tetracyclines (chlortetracycline, doxycycline, oxytetracycline, and tetracycline) in nontarget feed at a μg/kg level.
Validation of the method was performed according to the guideline included in the Commission Decision 2002/657/EC for official method.
The validated method was successfully applied to 50 feed samples collected from different milk farms and 25 samples obtained from feed manufacturers.
While oxytetracycline was the tetracycline most frequently detected, chlortetracycline was the analyte measured at the highest concentration 15.14 mg/Kg.
From 75 nonmedicated feed analysed 15% resulted to be positive for the presence of one tetracycline.
American Psychological Association (APA)
Gavilán, Rosa E.& Nebot, Carolina& Veiga-Gómez, Maria& Roca-Saavedra, Paula& Vazquez Belda, Beatriz& Franco, Carlos M.…[et al.]. 2016. A Confirmatory Method Based on HPLC-MSMS for the Detection and Quantification of Residue of Tetracyclines in Nonmedicated Feed. Journal of Analytical Methods in Chemistry،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107258
Modern Language Association (MLA)
Gavilán, Rosa E.…[et al.]. A Confirmatory Method Based on HPLC-MSMS for the Detection and Quantification of Residue of Tetracyclines in Nonmedicated Feed. Journal of Analytical Methods in Chemistry No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1107258
American Medical Association (AMA)
Gavilán, Rosa E.& Nebot, Carolina& Veiga-Gómez, Maria& Roca-Saavedra, Paula& Vazquez Belda, Beatriz& Franco, Carlos M.…[et al.]. A Confirmatory Method Based on HPLC-MSMS for the Detection and Quantification of Residue of Tetracyclines in Nonmedicated Feed. Journal of Analytical Methods in Chemistry. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107258
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1107258