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The Structures, Spectroscopic Properties, and Photodynamic Reactions of Three [RuCl(QN)NO]− Complexes (HQN = 8-Hydroxyquinoline and Its Derivatives) as Potential NO-Donating Drugs
Joint Authors
Xie, Leilei
Liu, Lifang
Wang, Wenming
Ma, Zhiou
Xu, Liqun
Zhao, Xuan
Wang, Hongfei
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The structures and spectral properties of three ruthenium complexes with 8-hydroxyquinoline (Hhqn) and their derivatives 2-methyl-8-quinolinoline (H2mqn) and 2-chloro-8-quiolinoline (H2cqn) as ligands (QN = hqn, 2mqn, or 2cqn) were calculated with density functional theory (DFT) at the B3LYP level.
The UV-Vis and IR spectra of the three [RuCl(QN)NO]− complexes were theoretically assigned via DFT calculations.
The calculated spectra reasonably correspond to the experimentally measured spectra.
Photoinduced NO release was confirmed through spin trapping of the electron paramagnetic resonance spectroscopy (EPR), and the dynamic process of the NO dissociation upon photoirradiation was monitored using time-resolved infrared (IR) spectroscopy.
Moreover, the energy levels and related components of frontier orbitals were further analyzed to understand the electronic effects of the substituent groups at the 2nd position of the ligands on their photochemical reactivity.
This study provides the basis for the design of NO donors with potential applications in photodynamic therapy.
American Psychological Association (APA)
Xie, Leilei& Liu, Lifang& Ma, Zhiou& Xu, Liqun& Zhao, Xuan& Wang, Hongfei…[et al.]. 2018. The Structures, Spectroscopic Properties, and Photodynamic Reactions of Three [RuCl(QN)NO]− Complexes (HQN = 8-Hydroxyquinoline and Its Derivatives) as Potential NO-Donating Drugs. Bioinorganic Chemistry and Applications،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1123184
Modern Language Association (MLA)
Ma, Zhiou…[et al.]. The Structures, Spectroscopic Properties, and Photodynamic Reactions of Three [RuCl(QN)NO]− Complexes (HQN = 8-Hydroxyquinoline and Its Derivatives) as Potential NO-Donating Drugs. Bioinorganic Chemistry and Applications No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1123184
American Medical Association (AMA)
Xie, Leilei& Liu, Lifang& Ma, Zhiou& Xu, Liqun& Zhao, Xuan& Wang, Hongfei…[et al.]. The Structures, Spectroscopic Properties, and Photodynamic Reactions of Three [RuCl(QN)NO]− Complexes (HQN = 8-Hydroxyquinoline and Its Derivatives) as Potential NO-Donating Drugs. Bioinorganic Chemistry and Applications. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1123184
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123184