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Prediction of Apoptosis Protein Subcellular Localization with Multilayer Sparse Coding and Oversampling Approach
Joint Authors
Chen, Xingjian
Hu, Xuejiao
Yi, Wenxin
Zou, Xiang
Xue, Wei
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The prediction of apoptosis protein subcellular localization plays an important role in understanding the progress in cell proliferation and death.
Recently computational approaches to this issue have become very popular, since the traditional biological experiments are so costly and time-consuming that they cannot catch up with the growth rate of sequence data anymore.
In order to improve the prediction accuracy of apoptosis protein subcellular localization, we proposed a sparse coding method combined with traditional feature extraction algorithm to complete the sparse representation of apoptosis protein sequences, using multilayer pooling based on different sizes of dictionaries to integrate the processed features, as well as oversampling approach to decrease the influences caused by unbalanced data sets.
Then the extracted features were input to a support vector machine to predict the subcellular localization of the apoptosis protein.
The experiment results obtained by Jackknife test on two benchmark data sets indicate that our method can significantly improve the accuracy of the apoptosis protein subcellular localization prediction.
American Psychological Association (APA)
Chen, Xingjian& Hu, Xuejiao& Yi, Wenxin& Zou, Xiang& Xue, Wei. 2019. Prediction of Apoptosis Protein Subcellular Localization with Multilayer Sparse Coding and Oversampling Approach. BioMed Research International،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1123829
Modern Language Association (MLA)
Chen, Xingjian…[et al.]. Prediction of Apoptosis Protein Subcellular Localization with Multilayer Sparse Coding and Oversampling Approach. BioMed Research International No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1123829
American Medical Association (AMA)
Chen, Xingjian& Hu, Xuejiao& Yi, Wenxin& Zou, Xiang& Xue, Wei. Prediction of Apoptosis Protein Subcellular Localization with Multilayer Sparse Coding and Oversampling Approach. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1123829
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123829