Analyzing the Relationship between Cohort and Case-Control Study Results Based on Model for Multiple Pathogenic Factors
Author
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
Although the relative risk from a prospective cohort study is numerically approximate to the odds ratio from a case-control study for a low-probability event, a definite relationship between case-control and cohort studies cannot be confirmed.
In this study, we established a different model to determine the relationship between case-control and cohort studies.
Methods.
Two analysis models (the cross-sectional model and multiple pathogenic factor model) were established.
Incidences in both the exposure group and the nonexposure group in a cohort study were compared with the frequency of the observed factor in each group (diseased and nondiseased) in a case-control study.
Results.
The relationship between the results of a case-control study and a cohort study is as follows: Pe=Pd∗m/Pc∗1−m+Pd∗m; Pn=m∗1−Pd/1−Pc∗1−m−Pd∗m, where Pe and Pn represent the incidence in the exposed group and nonexposed group, respectively, from the cohort study, while Pd and Pc represent the observed frequencies in the disease group and the control group, respectively, for the case-control study; finally, m represents the incidence in the total population.
Conclusions.
There is a definite relationship between the results of case-control and cohort studies assessing the same exposure.
The outcomes of case-control studies can be translated into cohort study data.
American Psychological Association (APA)
Liu, Hui. 2019. Analyzing the Relationship between Cohort and Case-Control Study Results Based on Model for Multiple Pathogenic Factors. Computational and Mathematical Methods in Medicine،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1130698
Modern Language Association (MLA)
Liu, Hui. Analyzing the Relationship between Cohort and Case-Control Study Results Based on Model for Multiple Pathogenic Factors. Computational and Mathematical Methods in Medicine No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1130698
American Medical Association (AMA)
Liu, Hui. Analyzing the Relationship between Cohort and Case-Control Study Results Based on Model for Multiple Pathogenic Factors. Computational and Mathematical Methods in Medicine. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1130698
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130698