The Roles of Thrombospondins in Hemorrhagic Stroke

Joint Authors

Wu, Xuan
Luo, Xu
Zhu, Qiquan
Zhang, Jie
Liu, Yun
Luo, Hansheng
Cheng, Yuan
Xie, Zongyi

Source

BioMed Research International

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-10-30

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Medicine

Abstract EN

Hemorrhagic stroke is a devastating cerebrovascular disease with significant morbidity and mortality worldwide.

Thrombospondins (TSPs), as matricellular proteins, belong to the TSP family which is comprised of five members.

All TSPs modulate a variety of cellular functions by binding to various receptors.

Recently, TSPs gained attention in the area of hemorrhagic stroke, especially TSP-1.

TSP-1 participates in angiogenesis, the inflammatory response, apoptosis, and fibrosis after hemorrhagic stroke through binding to various molecules including but not limited to CD36, CD47, and TGF-β.

In this review, we will discuss the roles of TSPs in hemorrhagic stroke and focus primarily on TSP-1.

American Psychological Association (APA)

Wu, Xuan& Luo, Xu& Zhu, Qiquan& Zhang, Jie& Liu, Yun& Luo, Hansheng…[et al.]. 2017. The Roles of Thrombospondins in Hemorrhagic Stroke. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139074

Modern Language Association (MLA)

Wu, Xuan…[et al.]. The Roles of Thrombospondins in Hemorrhagic Stroke. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1139074

American Medical Association (AMA)

Wu, Xuan& Luo, Xu& Zhu, Qiquan& Zhang, Jie& Liu, Yun& Luo, Hansheng…[et al.]. The Roles of Thrombospondins in Hemorrhagic Stroke. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139074

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1139074