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Comparison of Ramosetron with Palonosetron for Prevention of Postoperative Nausea and Vomiting in Patients Receiving Opioid-Based Intravenous Patient-Controlled Analgesia after Gynecological Laparoscopy
Joint Authors
Ahn, Eun Jin
Choi, Geun Joo
Kang, Hyun
Baek, Chong Wha
Jung, Yong Hun
Woo, Young Cheol
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We aimed to compare the effects of ramosetron and palonosetron in the prevention of postoperative nausea and vomiting (PONV) in patients that received opioid-based intravenous patient-controlled analgesia (IV-PCA) after gynecological laparoscopy.
We reviewed the electronic medical records of 755 adults.
Patients were classified into two groups, ramosetron (group R, n=589) versus palonosetron (group P, n=166).
Based on their confounding factors, 152 subjects in each group were selected after the implementation of propensity score matching.
The overall incidence of PONV at postoperative day (POD) 0 was lower in group R compared to group P (26.9% versus 36.8%; P=0.043).
The severity of nausea was lower in group R than in group P on postoperative day (POD) 0 (P=0.012).
Also, the complete responder proportion of patients was significantly higher in group R compared to that in group P on POD 0 (P=0.043).
In conclusion, ramosetron showed a greater efficacy in the prevention of postoperative nausea at POD 0 compared to palonosetron in patients after gynecological laparoscopy.
American Psychological Association (APA)
Ahn, Eun Jin& Choi, Geun Joo& Kang, Hyun& Baek, Chong Wha& Jung, Yong Hun& Woo, Young Cheol. 2017. Comparison of Ramosetron with Palonosetron for Prevention of Postoperative Nausea and Vomiting in Patients Receiving Opioid-Based Intravenous Patient-Controlled Analgesia after Gynecological Laparoscopy. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139474
Modern Language Association (MLA)
Ahn, Eun Jin…[et al.]. Comparison of Ramosetron with Palonosetron for Prevention of Postoperative Nausea and Vomiting in Patients Receiving Opioid-Based Intravenous Patient-Controlled Analgesia after Gynecological Laparoscopy. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1139474
American Medical Association (AMA)
Ahn, Eun Jin& Choi, Geun Joo& Kang, Hyun& Baek, Chong Wha& Jung, Yong Hun& Woo, Young Cheol. Comparison of Ramosetron with Palonosetron for Prevention of Postoperative Nausea and Vomiting in Patients Receiving Opioid-Based Intravenous Patient-Controlled Analgesia after Gynecological Laparoscopy. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139474
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139474