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A First Case Report of Subependymoma in PTPN11 Mutation-Associated Noonan Syndrome
Joint Authors
Boonyawat, Boonchai
Charoenpitakchai, Mongkon
Suwanpakdee, Piradee
Source
Case Reports in Neurological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Noonan syndrome (NS) is an autosomal dominant disorder in some cases caused by PTPN11 mutations.
Since somatic mutations in PTPN11 are seen in several tumor types, NS which causes germline PTPN11 mutations are also increase the risk of hematologic malignancies and brain solid tumors.
However, the report of brain tumors in Noonan syndrome remains rather rare.
Here, we report the first case of an 11-year-old Thai boy with Noonan syndrome who presented with symptoms related to hydrocephalus secondary to subependymoma in the fourth ventricle, and PTPN11 mutation was identified in this patient.
American Psychological Association (APA)
Boonyawat, Boonchai& Charoenpitakchai, Mongkon& Suwanpakdee, Piradee. 2019. A First Case Report of Subependymoma in PTPN11 Mutation-Associated Noonan Syndrome. Case Reports in Neurological Medicine،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1141344
Modern Language Association (MLA)
Boonyawat, Boonchai…[et al.]. A First Case Report of Subependymoma in PTPN11 Mutation-Associated Noonan Syndrome. Case Reports in Neurological Medicine No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1141344
American Medical Association (AMA)
Boonyawat, Boonchai& Charoenpitakchai, Mongkon& Suwanpakdee, Piradee. A First Case Report of Subependymoma in PTPN11 Mutation-Associated Noonan Syndrome. Case Reports in Neurological Medicine. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1141344
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141344