Successful Treatment of Crizotinib-Induced Fulminant Liver Failure: A Case Report and Review of Literature
Joint Authors
Kothadia, Jiten P.
Nair, Satheesh
Kreitman, Kyle
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Crizotinib is a first-line tyrosine kinase inhibitor used for the treatment of metastatic lung cancer.
Crizotinib-induced hepatotoxicity is a rare event.
We report a case of a 46-year-old female with a history of metastatic lung cancer who presented with acute liver failure after being on crizotinib for two months.
The medication was discontinued, and she was treated with N-acetylcysteine for seven days.
Her liver function tests returned to normal limits after 26 days after admission.
The precise mechanism and risk factors of crizotinib-induced hepatotoxicity remain unknown.
Physicians should be aware of the potentially lethal side effect caused by crizotinib.
American Psychological Association (APA)
Kreitman, Kyle& Nair, Satheesh& Kothadia, Jiten P.. 2020. Successful Treatment of Crizotinib-Induced Fulminant Liver Failure: A Case Report and Review of Literature. Case Reports in Hepatology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147946
Modern Language Association (MLA)
Kreitman, Kyle…[et al.]. Successful Treatment of Crizotinib-Induced Fulminant Liver Failure: A Case Report and Review of Literature. Case Reports in Hepatology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1147946
American Medical Association (AMA)
Kreitman, Kyle& Nair, Satheesh& Kothadia, Jiten P.. Successful Treatment of Crizotinib-Induced Fulminant Liver Failure: A Case Report and Review of Literature. Case Reports in Hepatology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147946
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147946
