Neurodisability with Severe Restriction of Mobility Is Associated with Reduced Serum Creatinine Values
Joint Authors
Eisenhut, Michael
Lim, Chun
Phillips, Marianne
Watson, Liam
Source
International Journal of Pediatrics
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
We investigated whether reduced mobility is associated with a reduction in serum creatinine in otherwise well children with neurodisability.
Materials and Methods.
This was a record based retrospective study and creatinine levels of children in groups with Gross Motor Function Classification System (GMFCS) category 1, 2, or 3 (group I); GMFCS 4 or 5 (group II); and age matched controls (group III) were compared.
Results.
Creatinine values were significantly different (p=0.002) between patients with neurodisability (mean 32.0 (SD 9.3), n=88) compared to patients without (mean 36.5 SD (9.8), n=88).
There was no significant difference in creatinine levels (p=0.684) between group I (mean 35.6 (9.1), n=23) and group III (mean 36.5 (9.8), n=88).
A significantly lower creatinine level (p<0.001) was found in group II (mean 30.7 (9.1), n=65) compared to group III and group I compared to group II (p=0.034).
Creatinine levels were with a mean (SD) of 25.7 (4.1) micromol/l significantly lower in patients with GMFCS 4 or 5 who died (n=4) compared to survivors (31.1 (3.6)), (p=0.04, n=61).
Conclusions.
Children with neurodisability with severe mobility restriction had a significantly lower serum creatinine compared to controls with less severe or no neurodisability.
Death in severe neurodisability may be associated with lower creatinine levels.
American Psychological Association (APA)
Lim, Chun& Phillips, Marianne& Watson, Liam& Eisenhut, Michael. 2019. Neurodisability with Severe Restriction of Mobility Is Associated with Reduced Serum Creatinine Values. International Journal of Pediatrics،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1167568
Modern Language Association (MLA)
Lim, Chun…[et al.]. Neurodisability with Severe Restriction of Mobility Is Associated with Reduced Serum Creatinine Values. International Journal of Pediatrics No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1167568
American Medical Association (AMA)
Lim, Chun& Phillips, Marianne& Watson, Liam& Eisenhut, Michael. Neurodisability with Severe Restriction of Mobility Is Associated with Reduced Serum Creatinine Values. International Journal of Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1167568
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167568