Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection
Joint Authors
Ruman, Marek
Namieśnik, Jacek
Jaszczak, Ewa
Narkowicz, Sylwia
Polkowska, Żaneta
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A simple and accurate ion chromatography (IC) method with pulsed amperometric detection (PAD) was proposed for the determination of cyanide ion in urine, sweat, and saliva samples.
The sample pretreatment relies on alkaline digestion and application of Dionex OnGuard II H cartridge.
Under the optimized conditions, the method showed good linearity in the range of 1–100 μg/L for urine, 5–100 μg/L for saliva, and 3–100 μg/L for sweat samples with determination coefficients (R)>0.992.
Low detection limits (LODs) in the range of 1.8 μg/L, 5.1 μg/L, and 5.8 μg/L for urine, saliva, and sweat samples, respectively, and good repeatability (CV < 3%, n=3) were obtained.
The proposed method has been successfully applied to the analysis of human biological samples.
American Psychological Association (APA)
Jaszczak, Ewa& Ruman, Marek& Narkowicz, Sylwia& Namieśnik, Jacek& Polkowska, Żaneta. 2017. Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection. Journal of Analytical Methods in Chemistry،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1170287
Modern Language Association (MLA)
Jaszczak, Ewa…[et al.]. Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection. Journal of Analytical Methods in Chemistry No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1170287
American Medical Association (AMA)
Jaszczak, Ewa& Ruman, Marek& Narkowicz, Sylwia& Namieśnik, Jacek& Polkowska, Żaneta. Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection. Journal of Analytical Methods in Chemistry. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1170287
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1170287