![](/images/graphics-bg.png)
Enhancing the Solubility of Curcumin Metal Complexes and Investigating Some of Their Biological Activities
Joint Authors
Quang Hieu, Tran
Thao, Doan Thi Thanh
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This article describes the synthesis of curcumin complexes with metal ions.
Properties of these complexes such as spectra IR and UV-Vis and solubility were investigated.
The optimum parameters of ultrasound to enhance the solubility was figured out as follows: the capacity of ultrasound: 750 W/g; the time of ultrasound: 7 min; the concentration of the surfactant Tween 80 : 2%.
The maximum solubility (mg/ml) of complexes was as follows: Cur-Fe(III): 0.162 ± 0.01; Cur-Zn(II): 0.267 ± 0.02; and Cur-Ca(II): 0.417 ± 0.05.
Antioxidant capacity (DPPH, %I) of curcumin complexes was higher than that of curcumin-free complexes.
All of these curcumin complexes revealed antimicrobial activities, in which calcium complex had the best resistance against Salmonella, followed by Fe(III) complexes.
Meanwhile, the zinc complex was not resistant to this bacterium.
These complexes showed antibacterial activity on Staphylococcus aureus, in which Cur-Ca (II) complexes had the highest antibacterial activity.
For Escherichia coli, the Cur-Zn (II) complex had no resistance, while the Cur-Ca (II) complex showed the highest antibacterial activity.
American Psychological Association (APA)
Quang Hieu, Tran& Thao, Doan Thi Thanh. 2019. Enhancing the Solubility of Curcumin Metal Complexes and Investigating Some of Their Biological Activities. Journal of Chemistry،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1171769
Modern Language Association (MLA)
Quang Hieu, Tran& Thao, Doan Thi Thanh. Enhancing the Solubility of Curcumin Metal Complexes and Investigating Some of Their Biological Activities. Journal of Chemistry No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1171769
American Medical Association (AMA)
Quang Hieu, Tran& Thao, Doan Thi Thanh. Enhancing the Solubility of Curcumin Metal Complexes and Investigating Some of Their Biological Activities. Journal of Chemistry. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1171769
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1171769