Synthesis, Characterization, and Tautomerism of 1,3-Dimethyl Pyrimidine-2,4,6-Trione s-Triazinyl HydrazineHydrazone Derivatives
Joint Authors
Sharma, Anamika
Jad, Yahya
Torre, Beatriz G. de la
Albericio, Fernando
El-Faham, Ayman
Siddiqui, M. Rafiq H.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
1,3,5-Triazines and pyrimidine-2,4,6-triones belong to that class of compounds which are well known in literature for possessing wide range of biological activities.
Here, we report a new family of compounds that encompasses these two structures.
The union of both heterocycles was carried out through a hydrazone moiety incorporated into an acetyl group at the position 5 of 1,3-dimethyl pyrimidine derivative.
The synthetic strategy adopted allowed the preparation of the target compounds with excellent yields and good purities.
The synthesized compounds were well characterized by NMR (1H and 13C), HRMS, and elemental analysis.
Furthermore, the tautomerism of enhydrazine versus hydrazone has also been studied.
American Psychological Association (APA)
Sharma, Anamika& Jad, Yahya& Siddiqui, M. Rafiq H.& Torre, Beatriz G. de la& Albericio, Fernando& El-Faham, Ayman. 2017. Synthesis, Characterization, and Tautomerism of 1,3-Dimethyl Pyrimidine-2,4,6-Trione s-Triazinyl HydrazineHydrazone Derivatives. Journal of Chemistry،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1172032
Modern Language Association (MLA)
Sharma, Anamika…[et al.]. Synthesis, Characterization, and Tautomerism of 1,3-Dimethyl Pyrimidine-2,4,6-Trione s-Triazinyl HydrazineHydrazone Derivatives. Journal of Chemistry No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1172032
American Medical Association (AMA)
Sharma, Anamika& Jad, Yahya& Siddiqui, M. Rafiq H.& Torre, Beatriz G. de la& Albericio, Fernando& El-Faham, Ayman. Synthesis, Characterization, and Tautomerism of 1,3-Dimethyl Pyrimidine-2,4,6-Trione s-Triazinyl HydrazineHydrazone Derivatives. Journal of Chemistry. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1172032
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172032