Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process
Joint Authors
Jin, Chen
Zhu, Weifeng
Shi, Tiannv
Guan, Yongmei
Chen, Lihua
Huang, Shiyu
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Product quality control is a prerequisite for ensuring safety, effectiveness, and stability.
However, because of the different strain species and fermentation processes, there was a significant difference in quality.
As a result, they should be clearly distinguished in clinical use.
Among them, the fermentation process is critical to achieving consistent product quality.
This study aims to introduce near-infrared spectroscopy analysis technology into the production process of fermented Cordyceps powder, including strain culture, strain passage, strain fermentation, strain filtration, strain drying, strain pulverizing, and strain mixing.
First, high performance liquid chromatography (HPLC) was used to measure the total nucleosides content in the production process of 30 batches of fermented Cordyceps powder, including uracil, uridine, adenine, guanosine, adenosine, and the process stability and interbatch consistency were analyzed with traditional Chinese medicine (TCM) fingerprinting, followed by the near-infrared spectroscopy (NIRS) combined with partial least squares regression (PLSR) to establish a quantitative analysis model of total nucleosides for online process monitoring of fermented Cordyceps powder preparation products.
The model parameters indicate that the established model with good robustness and high measurement precision.
It further clarifies that the model can be used for online process monitoring of fermented Cordyceps powder preparation products.
American Psychological Association (APA)
Shi, Tiannv& Guan, Yongmei& Chen, Lihua& Huang, Shiyu& Zhu, Weifeng& Jin, Chen. 2020. Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process. Journal of Analytical Methods in Chemistry،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1174955
Modern Language Association (MLA)
Shi, Tiannv…[et al.]. Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process. Journal of Analytical Methods in Chemistry No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1174955
American Medical Association (AMA)
Shi, Tiannv& Guan, Yongmei& Chen, Lihua& Huang, Shiyu& Zhu, Weifeng& Jin, Chen. Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process. Journal of Analytical Methods in Chemistry. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1174955
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174955