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Simultaneous Functional and Morphological Assessment of Left Atrial Appendage by 3D Virtual Models
Joint Authors
Landini, Luigi
Berti, Sergio
Vivoli, Giorgia
Gasparotti, Emanuele
Rezzaghi, Marco
Cerone, Elisa
Mariani, Massimiliano
Celi, Simona
Positano, Vincenzo
Source
Journal of Healthcare Engineering
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
The left atrial appendage (LAA) is responsible for thrombus formation in patients with atrial fibrillation.
The evaluation of both LAA function and morphology is crucial for the patient characterization and the preprocedural planning of LAA closure intervention.
Despite the availability of 3D imaging modalities, the current standard image analysis is based on manual delineation of the LAA contours on 2D views.
Methods.
In this study, a comprehensive approach based on a full 3D analysis of the tomographic dataset by surface extraction and processing (3D-S) is presented.
The proposed method allows extracting functional and morphologic information in the entire cardiac cycle by minimalizing manual user interaction.
The proposed methodology has been validated on ten computer tomography datasets.
Results.
The proposed 3D-S method was feasible in all cases.
Reproducibility was improved with respect to the reference 2D manual procedure (2D-S) (coefficient of variation 2.9 vs.
4.1% for diastolic ostium area; 3.8 vs.
6.1% for systolic ostium area; 2.4 vs.
5.3% for diastolic LAA volume; 2.7 vs.
5.9% for systolic LAA volume; and 7.7 vs.
17.1% for LAA ejection fraction).
No significant differences were found between 2D-S and 3D-S measurements.
Conclusions.
In this study, we introduced a fully 3D approach for LAA characterization, allowing the simultaneous assessment of LAA function and geometry.
The proposed approach could be used to improve the patient selection and the best sizing of the device for LAA closure and to allow a patient-specific 3D printing.
American Psychological Association (APA)
Vivoli, Giorgia& Gasparotti, Emanuele& Rezzaghi, Marco& Cerone, Elisa& Mariani, Massimiliano& Landini, Luigi…[et al.]. 2019. Simultaneous Functional and Morphological Assessment of Left Atrial Appendage by 3D Virtual Models. Journal of Healthcare Engineering،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1175335
Modern Language Association (MLA)
Vivoli, Giorgia…[et al.]. Simultaneous Functional and Morphological Assessment of Left Atrial Appendage by 3D Virtual Models. Journal of Healthcare Engineering No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1175335
American Medical Association (AMA)
Vivoli, Giorgia& Gasparotti, Emanuele& Rezzaghi, Marco& Cerone, Elisa& Mariani, Massimiliano& Landini, Luigi…[et al.]. Simultaneous Functional and Morphological Assessment of Left Atrial Appendage by 3D Virtual Models. Journal of Healthcare Engineering. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1175335
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175335