Osteosarcopenic Visceral Obesity and Osteosarcopenic Subcutaneous Obesity, Two New Phenotypes of Sarcopenia: Prevalence, Metabolic Profile, and Risk Factors
Joint Authors
Rondanelli, Mariangela
Faliva, Milena
Nichetti, M.
Avanzato, Ilaria
Spadaccini, Daniele
Perna, Simone
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-16
Country of Publication
Egypt
No. of Pages
8
Abstract EN
Background.
The main criticism of the definition of “osteosarcopenic obesity” (OSO) is the lack of division between subcutaneous and visceral fat.
This study describes the prevalence, metabolic profile, and risk factors of two new phenotypes of sarcopenia: osteosarcopenic visceral obesity (OSVAT) and osteosarcopenic subcutaneous obesity (OSSAT).
Methods.
A standardized geriatric assessment was performed by anthropometric and biochemical measures.
Dual-energy X-ray absorptiometry (DXA) was used to assess body composition, visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), osteoporosis, and sarcopenia.
Results.
A sample of 801 subjects were assessed (247 men; 554 women).
The prevalence of osteosarcopenic obesity (OSO) was 6.79%; OSSAT and OSOVAT were, respectively, 2.22% and 4.56%.
OSVAT (versus the others) showed a higher level of inflammation (CRP and ESR, p<0.05), bilirubin (p<0.05), and risk of fractures (FRAX index over 15%, p<0.001).
Subjects with OSSAT did not show any significant risk factors associated to obesity.
Conclusions.
The osteosarcopenic visceral obesity phenotype (OSVAT) seems to be associated with a higher risk of fractures, inflammation, and a worse metabolic profile.
These conditions in OSVAT cohort are associated with an increase of visceral adipose tissue, while patients with OSSAT seem to benefit related to the “obesity paradox.”
American Psychological Association (APA)
Perna, Simone& Spadaccini, Daniele& Nichetti, M.& Avanzato, Ilaria& Faliva, Milena& Rondanelli, Mariangela. 2018. Osteosarcopenic Visceral Obesity and Osteosarcopenic Subcutaneous Obesity, Two New Phenotypes of Sarcopenia: Prevalence, Metabolic Profile, and Risk Factors. Journal of Aging Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1180759
Modern Language Association (MLA)
Perna, Simone…[et al.]. Osteosarcopenic Visceral Obesity and Osteosarcopenic Subcutaneous Obesity, Two New Phenotypes of Sarcopenia: Prevalence, Metabolic Profile, and Risk Factors. Journal of Aging Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1180759
American Medical Association (AMA)
Perna, Simone& Spadaccini, Daniele& Nichetti, M.& Avanzato, Ilaria& Faliva, Milena& Rondanelli, Mariangela. Osteosarcopenic Visceral Obesity and Osteosarcopenic Subcutaneous Obesity, Two New Phenotypes of Sarcopenia: Prevalence, Metabolic Profile, and Risk Factors. Journal of Aging Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1180759
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1180759