Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer
Joint Authors
Lu, Yue
Zhao, Shirui
Zhang, Xin-an
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A novel Mn2+-doped hollow Mn-HMAS aluminosilica (Mn-HMAS) nanoparticle for simultaneous T1-weighted magnetic resonance imaging and drug delivery was reported.
The magnetic resonance tests showed that the Mn-HMAS nanoparticles display an excellent T1-weighted magnetic resonance imaging effect with a high T1 relaxivity (r1) of 8.8 mM-1S-1.
The MTT assays showed that the Mn-HMAS-DOX nanoparticles possess a better tumour cell inhibition effect than DOX.
In addition, the Mn-HMAS nanoparticles also exhibit good stability and noncytotoxicity.
These results demonstrated that the Mn-HMAS nanoparticles can be applied for the loading and delivery of various drugs in medicine.
American Psychological Association (APA)
Lu, Yue& Zhao, Shirui& Zhang, Xin-an. 2019. Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer. Journal of Nanomaterials،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1182074
Modern Language Association (MLA)
Lu, Yue…[et al.]. Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer. Journal of Nanomaterials No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1182074
American Medical Association (AMA)
Lu, Yue& Zhao, Shirui& Zhang, Xin-an. Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer. Journal of Nanomaterials. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1182074
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182074