Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer

Joint Authors

Lu, Yue
Zhao, Shirui
Zhang, Xin-an

Source

Journal of Nanomaterials

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-11-03

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Chemistry
Civil Engineering

Abstract EN

A novel Mn2+-doped hollow Mn-HMAS aluminosilica (Mn-HMAS) nanoparticle for simultaneous T1-weighted magnetic resonance imaging and drug delivery was reported.

The magnetic resonance tests showed that the Mn-HMAS nanoparticles display an excellent T1-weighted magnetic resonance imaging effect with a high T1 relaxivity (r1) of 8.8 mM-1S-1.

The MTT assays showed that the Mn-HMAS-DOX nanoparticles possess a better tumour cell inhibition effect than DOX.

In addition, the Mn-HMAS nanoparticles also exhibit good stability and noncytotoxicity.

These results demonstrated that the Mn-HMAS nanoparticles can be applied for the loading and delivery of various drugs in medicine.

American Psychological Association (APA)

Lu, Yue& Zhao, Shirui& Zhang, Xin-an. 2019. Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer. Journal of Nanomaterials،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1182074

Modern Language Association (MLA)

Lu, Yue…[et al.]. Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer. Journal of Nanomaterials No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1182074

American Medical Association (AMA)

Lu, Yue& Zhao, Shirui& Zhang, Xin-an. Fabrication of Mn2+-Doped Hollow Mesoporous Aluminosilica Nanoparticles for Magnetic Resonance Imaging and Drug Delivery for Therapy of Colorectal Cancer. Journal of Nanomaterials. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1182074

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1182074