Inverse Occlusion: A Binocularly Motivated Treatment for Amblyopia
Joint Authors
Qu, Jia
Wu, Yidong
Zhou, Jiawei
Hess, Robert F.
He, Zhifen
Chen, Yiya
Chen, Xiaoxin
Liang, Yunjie
Mao, Yu
Yao, Zhimo
Lu, Fan
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-19
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Recent laboratory findings suggest that short-term patching of the amblyopic eye (i.e., inverse occlusion) results in a larger and more sustained improvement in the binocular balance compared with normal controls.
In this study, we investigate the cumulative effects of the short-term inverse occlusion in adults and old children with amblyopia.
This is a prospective cohort study of 18 amblyopes (10-35 years old; 2 with strabismus) who have been subjected to 2 hours/day of inverse occlusion for 2 months.
Patients who required refractive correction or whose refractive correction needed updating were given a 2-month period of refractive adaptation.
The primary outcome measure was the binocular balance which was measured using a phase combination task; the secondary outcome measures were the best-corrected visual acuity which was measured with a Tumbling E acuity chart and converted to logMAR units and the stereoacuity which was measured with the Random-dot preschool stereogram test.
The average binocular gain was 0.11 in terms of the effective contrast ratio (z=−2.344, p=0.019, 2-tailed related samples Wilcoxon Signed Rank Test).
The average acuity gain was 0.13 logMAR equivalent (t17=4.76, p<0.001, 2-tailed paired samples t-test).
The average stereoacuity gain was 339 arc seconds (z=−2.533, p=0.011).
Based on more recent research concerning adult ocular dominance plasticity, we conclude that inverse occlusion in adults and old children with amblyopia does produce long-term gains to binocular balance and that acuity and stereopsis can improve in some subjects.
American Psychological Association (APA)
Zhou, Jiawei& He, Zhifen& Wu, Yidong& Chen, Yiya& Chen, Xiaoxin& Liang, Yunjie…[et al.]. 2019. Inverse Occlusion: A Binocularly Motivated Treatment for Amblyopia. Neural Plasticity،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1201454
Modern Language Association (MLA)
Zhou, Jiawei…[et al.]. Inverse Occlusion: A Binocularly Motivated Treatment for Amblyopia. Neural Plasticity No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1201454
American Medical Association (AMA)
Zhou, Jiawei& He, Zhifen& Wu, Yidong& Chen, Yiya& Chen, Xiaoxin& Liang, Yunjie…[et al.]. Inverse Occlusion: A Binocularly Motivated Treatment for Amblyopia. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1201454
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201454