Potential effect of some fruit leaves to reduce weight in obese experimental animals

Abstract EN

This study was carried out to evaluate the effect of different levels of mulberry(Morus alba), fig(Ficus carica ), olive (Olea europaea) leaves as a source of anti-oxidant and phenolic compounds on body weight gain (BWG), food intake, feed efficiency ratio, lipid profile, kidney and liver function on obese rats.

Fourty male albino rats(Sprague dawley strain) weighting 170±3 were divided into two main groups; the first group (5rats) fed basal diet used as negative control group.

The second group (35 rats) obese rats were divided into 7 sub-groups (5per each); group (1) was fed on high fat diet( positive control group +ve), group 2, 3) were fed on high fat diet containing 2.5% and 5 % , dried mulberry leaves respectively.

group 4, 5 were fed on high fat diet containing 2.5% and 5 % , dried fig leaves respectively group 6, 7 were fed on high fat diet containing 2.5% and 5 % , dried olive leaves respectively.

The result revealed that, All treated groups showed a significant decreace.

BWG, FER, FI, T.

G, cholesterol, LDLc, VLDLc, liver enzymes (ALT, AST and ALP), uric acid, urea and creatinine.

However, all treated groups showed a significant increased HDLc as compared with positive control group.

it could be concluded that consumption of olive leaves 5% has a best significant treatment effect to improve lipid profile, kidney, liver function in obese rats