Potential protective effects of cauliflower leaves and prickly pear fruits skin on liver disorders induced by carbon tetrachloride in rats

Abstract EN

The present study aims to investigate the potential protective effects of food industries' by-products, cauliflower leaves, and prickly pear fruits skin, against liver disorders induced by carbon tetrachloride on experimental rats.

Thirty rats were distributed into five equal groups as follow: Group 1, control (normal) group, group 2, control positive group i.

e.

rats infected with hepatotoxicity by CCl₄, group 3, infected rats treated with 5% prickly pear peels powder (PPP), group 4, infected rats treated with 5% cauliflower leaves powder (CLP), group 5, infected rats treated with a mixture of 2.5% PPP plus 2.5% CLP.

CCl₄ induced a significant decrease (p≤0.05) in BWG (-54.40), FI (-36.36) and FER (- 23.33% ) compared to normal controls.

Supplementation of the diet with PPP, CLP, and their mixture induced a significant (p≤0.05) increase in body weight gain (BWG), feed intake (FI), and feed efficiency ratio (FER) by the ratio of 33.55, 40.39 and57.56% ; 23.35, 30.64 and 40.14% ; and 6.76, 14.01 and 16.42% of the control positive group, respectively.

Also, consumption of the all-tested plant parts improved the biological parameters Expressing liver functions examination and biological antioxidant (glutathione, GSH).

Reduced glutathione (GSH) as well as decreasing the formation of malonaldehyde (MDA) i.

e.

serum lipid peroxidation or oxidative stress. Furthermore, all the biochemical analyzes results were in agreement with the results of the histological examination.