Simple synthesis of some chromatographic stationary phases by the Sol-Gel method

Abstract EN

A simple method for the synthesis of some silicate-based polymers for use as chromatographic stationary phases is presented.

Consecutive hydrolysis and polycondensation of some organically modified silicon alkoxides result in the formation of polymeric matrices in about 100% yield with high surface loading of organic moieties.

The methyl, propyl, propylethylenediamine as well as other polymeric silicate derivatives were all prepared by this method.

The use of the proposed procedure assures minimal residual surface hydroxyl group functionalities, thus avoiding the need for, usually low yield, multiple end-capping reactions.

It was observed that the type of the catalyst and solvent used were important factors that influenced both the gelation time and gel transparency.

The effect of these factors was dependent on the nature of the precursor under consideration and generalizations were not possible.

The IR spectra of the synthesized polymeric matrices confirmed the formation of the desired product as well as the existence of very little of residual hydroxyl group functionalities