Transplacental passage of igg as a possible factor in pregnancy loss and initiation of labor

Other Title(s)

دور عبور الغلوبين المناعي G للمشيمة كعامل محتمل في فقدان الحمل و بدء المخاض

Source

Journal of the Arab Board of Health Specializations

Issue

Vol. 1, Issue 4 (31 Oct. 1999), pp.92-95, 4 p.

Publisher

The Arab Board of Health Specializations

Publication Date

1999-10-31

Country of Publication

Syria

No. of Pages

4

Main Subjects

Medicine

Abstract EN

Objective: To study the role of the transplacental passage of IgG in the initiation of labor or pregnancy loss.

Materials, and Methods: 62 women with spontaneous normal labor and 60 with elective Caesarean section at a large university hospital in Baghdad, Iraq were placed in a prospective study.

Sections of the placenta were prepared with a cryostat at 30oC, stained with a locally modified direct immunofluorescent technique, and studied with an irhmunofluorescent microscope to determine the density of IgG deposition.

The density was then quantified on a scale of 1-4.

Results: Immunofluorescent scores of IgG deposition in trophoblastic tissue were higher in cases of spontaneous labor (3.2 0.1) than in cases delivered electively before the onset of spontaneous labor (1.9 0.1, P<0.0001).

Linear regression revealed a significant increase in antibody deposition with advancing gestational age in both groups, being more clear in the spontaneous labor than in the elective Caesarean section group (r=0.6, Vs r=0.4, P=0.001) Conclusion: Higher IgG deposition was found in placental tissue as gestational age advanced.

At the point of highest IgG deposition, labor began.

This may suggest a role for transplacental IgG in the initiation of labor or earlier pregnancy loss.

American Psychological Association (APA)

Kubba, Qays& al-Musawi, Khalidah& al-Ani, Huda N.. 1999. Transplacental passage of igg as a possible factor in pregnancy loss and initiation of labor. Journal of the Arab Board of Health Specializations،Vol. 1, no. 4, pp.92-95.
https://search.emarefa.net/detail/BIM-157520

Modern Language Association (MLA)

Kubba, Qays…[et al.]. Transplacental passage of igg as a possible factor in pregnancy loss and initiation of labor. Journal of the Arab Board of Health Specializations Vol. 1, no. 4(October 1999), pp.92-95.
https://search.emarefa.net/detail/BIM-157520

American Medical Association (AMA)

Kubba, Qays& al-Musawi, Khalidah& al-Ani, Huda N.. Transplacental passage of igg as a possible factor in pregnancy loss and initiation of labor. Journal of the Arab Board of Health Specializations. 1999. Vol. 1, no. 4, pp.92-95.
https://search.emarefa.net/detail/BIM-157520

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 95

Record ID

BIM-157520