Effect of sanguinarine and vitamins ad3e on growth performance in cyprinus carpio

Abstract EN

A preliminary study was conducted to evaluate the effect of dietary supplementation of commercial product containing the isoquinoline alkaloid sanguinarine (Sangrovit®) by 50 g / ton ration, and Vitamins AD3E (Baytara®) by 2 ml / Kg ration on common carp (Cyprinus carpio) growth performance, haematological parameters, gut microbiota, biochemical parameter, and immunological parameter when infected with Aeromonas hydrophila and histopathological finding compared to the control group determined at 15 days intervals during the feeding trial.

Each dietary treatment had two replicate aquaria.

The results showed that during the period of experiment using these feed additives showed mild significant increase in growth performance (Weight gain, Average daily gain, Feed intake and Feed conversion ratio), except in sanguinarinE plus vitamins which showed highly significant (P < 0.05) increase specially at 45 days, meanwhile all groups showed non significant changes in Erythrogram and Leucogram except in sanguinarine supplemented group, there was mild increase.

All groups showed significant (P < 0.05) decrease in gut micobiota (total bacterial and coliform count) and also more resistance to challenge with Aeromonas hydro-phila.

In liver, kidney function and serum protein there were non significant changes along all periods except after infection with Aeromonas hydrophila, there where mild changes in these biochemical functions so the feed additives enhance the fish defense mechanism and elevates the responsibility of fish to disease.