The effect of tranexamic acid on bleeding during lumbar laminectomy

Abstract EN

A large volume of blood is lost during spinal surgery.

Blood and its products transfusion has risk far patients, so different methods are used to reduce bleeding and Traneyamic Acid (TA) is one, which has been used successfully in liver surgery and total knee arthroplasty.

It is not expensive and does not have serious side effects.

Studies on this drug in spine surgery are limited, Sixty patients 25-45 yrs of age were given randomly either tranexamic acid (10 mg/kg that was infused in half an hour) or placebo (Isotonic saim).

Perioperative management was standardized.

The total amount of blood transfused and intraoperative blood loss in the perioperative period was significantly reduced in the tranexamic group (P-0.044), Surgeon's satisfaction and operative field condition between 2 groups were significantly different.

The administration of prophylactic tranexamic acid in laminectomy patients has the potential to reduce perioperative blood loss and transfusion.