Assessment of antibacterial and antioxidant activities of methanolic extracts of euphorbia hierosolymitana, fritillaria libanotica, artemisia inculta and achillea santolina selected from Karak Region
Other Title(s)
تقييم النشاطية المضادة للبكتيريا والمضادة للأكسدة للمستخلصات الميثانولية لنباتات الحلبلوب و الشيح و جعدة الصبيان و الزنبق اللبناني و التي تم اختيارها من منطقة الكرك
Dissertant
Thesis advisor
al-Tarawinah, Khalid Ahmad Jafar
Comitee Members
al-Zaraini, Wail Ali Hasan
al-Shakanbah, Jumah Muti
al-Shahatit, Sulhi Faysal
University
Mutah University
Faculty
Faculty of Science
Department
Department of Biological Sciences
University Country
Jordan
Degree
Master
Degree Date
2013
Arabic Abstract
تناول البحث بالدراسة استيطان القبائل العربية و تواجدها في الفترة التي سبقت ظهور الإسلام ثم الفترة التي تلت الفتح الإسلامي للجزيرة الفراتية.
و جاء البحث مبينا تسمية الجزيرة و بيان حدودها و أهميتها الاقتصادية ثم البدايات الأولى لاستيطان القبائل العربية قبل الإسلام، ثم تطرق إلى مرحلة فتوح الجزيرة و أثر ذلك على توزيع القبائل و تواجدها و أخيرا مناطق استيطانها بعد الفتح و هجرة العديد من القبائل في عهد معاوية بن أبي سفيان و خصوصا القبائل القيسية، التي اتخذت من ضفاف الفرات العليا موطنا لها إلى جانب القبائل التي سبقتها في الاستيطان مثل بكر و تغلب و غيرها.
English Abstract
Fritillaria libanotica, Artemisia inculta, and Achillea santolina were selected from Al-karak region in order to investigate their antibacterial and antioxidant activities.
The antibacterial activity of these plants was carried out on five bacterial strain (S.
aureus, E.
coli, K.
pneumoniae, M.
luteus and B.
subtilis.
Their total phenolic contents were evaluated; the highest total phenol was observed in E.
hierosolymitanaa with 509.3 mg GAE / g plant extract followed by F.
libanotica, A.
inculta, and A.
santolina with 75.9, 221, and 203.7 mg / g plant extract, respectively.
The antioxidant activity was estimated using DPPH and FRAB methods, the highest antioxidant activity was obtained with E.
hierosolymitanaa extract and found to be 0.76 and 7.68 mg Trolox /g plant extract, respectively.
The lowest antioxidant activity was obtained with F.
libanotica in both methods which was 0.24 and 0.77 mg Trolox / g plant extract, respectively.
The lowest IC50 (highest antioxidant activity) was observed in E.
hierosolymitanaa with 0.98 mg / ml.
Intermediate effect observed in A.
inculta and A.
santolina with IC50 1.2 mg / ml.
The lowest antioxidant activity was obtained in F.
libanotica with IC50 3.02 mg / ml.
The MeOH extract of A.
santolina, E.
hierosolymitanaa and A.
inculta have the highest antibacterial activities against the pathogenic bacterial strains ; K.
pneumoniae, S.
aureus and M.
luteus.
Moreover, A.
inculta gave an advantage over the other plants as a reason of having the lowest minimum inhibition concentration (MIC) with 250-500 µg / ml.
E.
hierosolymitanaa extract was a potent source of natural antioxidant and antimicrobial ingredients.
Therefore, more investigation is recommended regarding this plant favoring their possible use in industrial pharmacology on large scale.
Main Subjects
Topics
No. of Pages
52
Table of Contents
Table of contents.
Abstract.
Chapter One : theoretical background.
Chapter Two : literature review.
Chapter Three : design and methodology.
Chapter Four : results, discussion and recommendation.
References.
American Psychological Association (APA)
al-Sarayirah, Ahmad Zal. (2013). Assessment of antibacterial and antioxidant activities of methanolic extracts of euphorbia hierosolymitana, fritillaria libanotica, artemisia inculta and achillea santolina selected from Karak Region. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-322642
Modern Language Association (MLA)
al-Sarayirah, Ahmad Zal. Assessment of antibacterial and antioxidant activities of methanolic extracts of euphorbia hierosolymitana, fritillaria libanotica, artemisia inculta and achillea santolina selected from Karak Region. (Master's theses Theses and Dissertations Master). Mutah University. (2013).
https://search.emarefa.net/detail/BIM-322642
American Medical Association (AMA)
al-Sarayirah, Ahmad Zal. (2013). Assessment of antibacterial and antioxidant activities of methanolic extracts of euphorbia hierosolymitana, fritillaria libanotica, artemisia inculta and achillea santolina selected from Karak Region. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-322642
Language
English
Data Type
Arab Theses
Record ID
BIM-322642
