A new keynote of hemorrhoids patients as oxidative stress indicators

Abstract EN

This study evaluated the effect of hemorrhoids on the levels of antioxidants such as vitamin E and C, as well as the malondialdehyde (MDA) levels as the end product of lipid peroxidation and peroxynitrite (ONOO-) levels as a parameter of peroxidative stress for 35 patients (20 males, 15 females) affected by hemorrhoids, before and after rubber band ligation by using baron band ligation device compared with healthy control groups of 35 (20 males, 15 females).

It has been found that the levels of vit.

E and C are significantly decreased, where as the MDA and peroxynitrite levels are increased among patients (males and females) before the treatment compared with controls, while the vitamins values are significantly increased when the MDA and peroxynitrite (ONOO-) levels are non significantly decreased after 7 days of treatment which is safe and easy procedure.

The results suggest that the measurement of lipid peroxidation and peroxidative product matched with evaluation of antioxidants, may be a best indictors for that hemorrhoids induce oxidative stress compared with healthy controls and the treatment, due to decrease of oxidative stress and tissue damage.