Chromosomal analysis and maternal age risk in some down syndrome patients
Other Title(s)
التحليل الكروموسومي و خطورة عمر الأمومة لبعض مرضى متلازمة داون
Joint Authors
al-Faysal, Abd al-Husayn Muwayt
Yasin, Ruqayah Ghayyath
Source
Iraqi Journal of Biotechnology
Issue
Vol. 12, Issue 2 (31 Dec. 2013), pp.114-124, 11 p.
Publisher
University of Baghdad Genetic Engineering and Biotechnology for Postgraduate Studies
Publication Date
2013-12-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Topics
Abstract AR
تم إجراء التحليل الكروموسومي لخمسين من مرضى متلازمة داون و قد بينت النتائج أن 88 % من المرضى يملكون ثلاثية كروموسوم 21 و 2% بانتقال كروموسومي 21 و 10 % موزائيكية لثلاثية كروموسوم 21.
كما بينت النتائج أن 72 % من المرضى بعمر 34-12 سنة و 26 % بعمر أكثر من 35 سنة و أن 2 % بعمر الأمومة 20-18 سنة و أن المتلازمة أكثر انتشارا بين الذكور من الإناث.
Abstract EN
Chromosomal analysis was done on 50 clinically diagnosed Down syndrome patients.
The karyotype analysis revealed that 88 % (44 of 50 cases) with trisomy 21, having three copies of chromosome 21.
In 2 % (one case) translocation was observed, one copy of chromosome 21 was translocated to another chromosome 21 and in 10 % (5 cases) there was a mosaicism for a trisomic.
The higher percentage (72 %) of cases was found between 21-34 years.
26 % of cases were found with ages above 35 years.
Only 2 % of cases were found with maternal age between18-20 years and Down syndrome is more frequent in males than in females.
American Psychological Association (APA)
al-Faysal, Abd al-Husayn Muwayt& Yasin, Ruqayah Ghayyath. 2013. Chromosomal analysis and maternal age risk in some down syndrome patients. Iraqi Journal of Biotechnology،Vol. 12, no. 2, pp.114-124.
https://search.emarefa.net/detail/BIM-342311
Modern Language Association (MLA)
al-Faysal, Abd al-Husayn Muwayt& Yasin, Ruqayah Ghayyath. Chromosomal analysis and maternal age risk in some down syndrome patients. Iraqi Journal of Biotechnology Vol. 12, no. 2 (2013), pp.114-124.
https://search.emarefa.net/detail/BIM-342311
American Medical Association (AMA)
al-Faysal, Abd al-Husayn Muwayt& Yasin, Ruqayah Ghayyath. Chromosomal analysis and maternal age risk in some down syndrome patients. Iraqi Journal of Biotechnology. 2013. Vol. 12, no. 2, pp.114-124.
https://search.emarefa.net/detail/BIM-342311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 122-124
Record ID
BIM-342311
