The relationship between the antioxidant system, oxidative stress and dialysis-related amyloidosis in hemodialysis patients
Joint Authors
Capriz, Irfan
Celik, Gulperi
Yontim, Mustafa
Bilge, Murat
Unald, Mustafa
Mehmetoglu, Idris
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 24, Issue 6 (31 Dec. 2013), pp.1157-1164, 8 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2013-12-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
End-stage renal disease (ESRD) is associated with several complications that are partly due to excess amounts of reactive oxygen species and / or decreased antioxidant activity.
Dialysis-related amyloidosis (DRA) has also been linked to increased oxidative stress.
The aim of this study was to investigate the relationships between the antioxidant system, including superoxide dismutase (SOD), malonyldialdehyde (MDA), various biochemical parameters and shoulder amyloidosis, in hemodialysis patients.
We studied 107 non-diabetic chronic dialysis patients.
The SOD levels correlated with right and left biceps tendon thickness (r = -0.219, P = 0.048 and r =0.236, P = 0.031, respectively), MDA (r = -0.429, P = 0.000) and albumin levels (r = -0.319, P = 0.001).
MDA levels correlated with right and left biceps thickness (r = 0.291, P = 0.006 and r = 0.337 P = 0.001, respectively) and β2microglobulin levels (r = 0.455, P = 0.000).
We also identified the statistically significant relationships between MDA levels and supraspinatus tendon thickening (greater than 7 mm) and right and left biceps tendon thickness (P = 0.022, P = 0.040 and P = 0.005, respectively).
Our data suggest the complex relationship between antioxidants and oxidative stress and further support the roles of oxidative stress and antioxidants in DRA.
American Psychological Association (APA)
Celik, Gulperi& Capriz, Irfan& Yontim, Mustafa& Bilge, Murat& Unald, Mustafa& Mehmetoglu, Idris. 2013. The relationship between the antioxidant system, oxidative stress and dialysis-related amyloidosis in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 24, no. 6, pp.1157-1164.
https://search.emarefa.net/detail/BIM-342562
Modern Language Association (MLA)
Capriz, Irfan…[et al.]. The relationship between the antioxidant system, oxidative stress and dialysis-related amyloidosis in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 24, no. 6 (2013), pp.1157-1164.
https://search.emarefa.net/detail/BIM-342562
American Medical Association (AMA)
Celik, Gulperi& Capriz, Irfan& Yontim, Mustafa& Bilge, Murat& Unald, Mustafa& Mehmetoglu, Idris. The relationship between the antioxidant system, oxidative stress and dialysis-related amyloidosis in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2013. Vol. 24, no. 6, pp.1157-1164.
https://search.emarefa.net/detail/BIM-342562
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1162-1164
Record ID
BIM-342562