Spectrophotometric method for the determination of captopril in pharmaceutical formulations

Other Title(s)

طريقة طيفية لتقدير الكابوتريل في المستحضرات الدوائية

Joint Authors

Muhammad, Dawud Habbu
Shihab, Intisar Adil
Ahmad, Hind

Source

Baghdad Science Journal

Issue

Vol. 10, Issue 3 (30 Sep. 2013), pp.965-970, 6 p.

Publisher

University of Baghdad College of Science for Women

Publication Date

2013-09-30

Country of Publication

Iraq

No. of Pages

6

Main Subjects

Pharmacy, Health & Medical Sciences

Topics

Abstract AR

تم تطوير طريقة طيفية بسيطة و سريعة و حساسة لتقدير الكابوتريل في المحلول المائي.

تعتمد الطريقة على تفاعل الكابوتريل مع -3,2ثنائي كلورو 4,1 نفثوكوينون في محيط متعادل لإعطاء ناتج ملون مستقر يظهرا على امتصاص عند 347 نانو ميتر و الامتصاصية المولارية 310 x 5.6 لتر.

مول1-.

سم1- تم تطبيق الطريقة و بنجاح في تقدير الكابوتريل في مستحضره الصيدلاني بشكل حبوب.

Abstract EN

A simple, rapid and sensitive spectrophotometric method has been developed for the determination of captopril in aqueous solution.

The method is based on reaction of captopril with 2, 3-dichloro 1, 4- naphthoquinon(Dichlone) in neutral medium to form a stable yellow colored product which shows maximum absorption at 347 nm with molar absorptivity of 5.6 ×103 L.mole-1.

cm-1.

The proposed method is applied successfully for determination of captopril in commercial pharmaceutical tablets.

American Psychological Association (APA)

Muhammad, Dawud Habbu& Shihab, Intisar Adil& Ahmad, Hind. 2013. Spectrophotometric method for the determination of captopril in pharmaceutical formulations. Baghdad Science Journal،Vol. 10, no. 3, pp.965-970.
https://search.emarefa.net/detail/BIM-343243

Modern Language Association (MLA)

Muhammad, Dawud Habbu…[et al.]. Spectrophotometric method for the determination of captopril in pharmaceutical formulations. Baghdad Science Journal Vol. 10, no. 3 (2013), pp.965-970.
https://search.emarefa.net/detail/BIM-343243

American Medical Association (AMA)

Muhammad, Dawud Habbu& Shihab, Intisar Adil& Ahmad, Hind. Spectrophotometric method for the determination of captopril in pharmaceutical formulations. Baghdad Science Journal. 2013. Vol. 10, no. 3, pp.965-970.
https://search.emarefa.net/detail/BIM-343243

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 968-970

Record ID

BIM-343243