![](/images/graphics-bg.png)
Spectrophotometric determination of rantidine-HCl in pharmaceutical formulations
Other Title(s)
التقدير الطيفي للرانتدين-هايدروكلوريد في المستحضرات الصيدلانية
Author
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 22, Issue 2 (30 Jun. 2009)8 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2009-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract AR
يتضمن البحث تطوير طريقة طيفية لتقدير الرانتدين -هيدروكلويد في الحبوب الدوائية.
تعتمد الطريقة على تفاعل DDQ و p-Cl مع الرانتدين -هيدروكلوريد لتكوين ناتج برتقالي محمر و قرمزي يعطي امتصاصية عند طول موجي قدره 460 و 540 نانوميتر لكل من p-Cl j DDQ على التوالي.
يشير الرسم البياني الخطي للامتصاص مقابل التركيز بأن قانون بير ينطق ضمن مدى التراكيز 20-160 و 30-120 مايكرو غرام / مل مع امتصاصية مولارية مساوية إلى2.631 × و 1.052 × 10 لتر.
مول -1.
سم -1 لكل من طريقة p-Cl DDQ على التوالي.
تمت دراسة الظروف المثلى للتفاعل و تطبق الطريقة على المستحضرات الصيدلانية.
Abstract EN
Spectrophotometric methods were developed for the determination of rantidine-HCl in pharmaceutical tablets.
These methods were based on the reaction of DDQ and p-chloranil with rantidine-HCl, res ulting in the formation of an orange-red and purple colored products which are quantified spectrophotometrically at 460 and 540nm in DDQ and p-chloranil, respectively.
A graph of absorbance versus concentration show that Beer’s law is obeyed in a concentration ranges of 20-160 and (30-120)g/ml with molar absorptivities of 2.631 x 103 and 1.052 x 103l .mol-1-cm-1 for DDQ and p-chloranil, respectively.
The optimum conditions for color development are described and the proposed methods were applied s atisfactory to pharmaceutical preparations.
American Psychological Association (APA)
Hammudi, Azhar Sadiq. 2009. Spectrophotometric determination of rantidine-HCl in pharmaceutical formulations. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 22, no. 2.
https://search.emarefa.net/detail/BIM-354906
Modern Language Association (MLA)
Hammudi, Azhar Sadiq. Spectrophotometric determination of rantidine-HCl in pharmaceutical formulations. Ibn al-Haitham Journal for Pure and Applied Science Vol. 22, no. 2 (2009).
https://search.emarefa.net/detail/BIM-354906
American Medical Association (AMA)
Hammudi, Azhar Sadiq. Spectrophotometric determination of rantidine-HCl in pharmaceutical formulations. Ibn al-Haitham Journal for Pure and Applied Science. 2009. Vol. 22, no. 2.
https://search.emarefa.net/detail/BIM-354906
Data Type
Journal Articles
Language
English
Notes
Includes appendices.
Record ID
BIM-354906