Evaluation of in vitro free radical scavenging potential of streptomyces sp. AM-S1 culture filtrate
Joint Authors
Sowndhararajan, Kandhasamy
Kang, Sun Chul
Source
Saudi Journal of Biological Sciences
Issue
Vol. 20, Issue 3 (31 Jul. 2013), pp.227-233, 7 p.
Publisher
Publication Date
2013-07-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
The present study was carried out to determine the free radical scavenging potential of culture filtrate of Streptomyces sp.
AM-S1.
Antioxidant activity of culture filtrate, lyophilized culture filtrate and ethyl acetate extract of Streptomyces sp.
AM-S1 was determined by various in vitro assays such as ferric reducing power assay, phosphomolybdenum reduction, DPPH and ABTS radical scavenging activities.
The results revealed that the culture filtrate of Streptomyces sp.
AM-S1 effectively scavenged DPPH (IC50 90.2 ll / ml) and ABTS (IC50 13.2 ll / ml) radicals in a concentration dependent manner.
In all the assays, ethyl acetate extract registered higher antioxidant activity when compared with the lyophilized culture filtrate (LCF).
In addition, ethyl acetate extract (1123.4 lmole Fe(II) / mg extract) exhibited higher ferric reducing activity than the standard BHA (814.4 lmole Fe(II) / mg extract).
Further works are needed on the isolation and identification of antioxidant molecules from the ethyl acetate extract of Streptomyces sp.
AM-S1 culture filtrate.
American Psychological Association (APA)
Sowndhararajan, Kandhasamy& Kang, Sun Chul. 2013. Evaluation of in vitro free radical scavenging potential of streptomyces sp. AM-S1 culture filtrate. Saudi Journal of Biological Sciences،Vol. 20, no. 3, pp.227-233.
https://search.emarefa.net/detail/BIM-358280
Modern Language Association (MLA)
Sowndhararajan, Kandhasamy& Kang, Sun Chul. Evaluation of in vitro free radical scavenging potential of streptomyces sp. AM-S1 culture filtrate. Saudi Journal of Biological Sciences Vol. 20, no. 3 (Jul. 2013), pp.227-233.
https://search.emarefa.net/detail/BIM-358280
American Medical Association (AMA)
Sowndhararajan, Kandhasamy& Kang, Sun Chul. Evaluation of in vitro free radical scavenging potential of streptomyces sp. AM-S1 culture filtrate. Saudi Journal of Biological Sciences. 2013. Vol. 20, no. 3, pp.227-233.
https://search.emarefa.net/detail/BIM-358280
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 232-233
Record ID
BIM-358280