Synthesis of monosaccharides

Dissertant

Abd al-Rahman, Sittanah Ahmad al-Khatim

Thesis advisor

Muhammad, Mubarak al-Sayyid Uthman

Comitee Members

Husayn, Muhammad Ali
al-Tuhami, Mahjub Sharif

University

Omdurman Islamic University

Faculty

Faculty of Pharmacy

Department

Department of Pharmaceutical Chemistry

University Country

Sudan

Degree

Ph.D.

Degree Date

2012

English Abstract

A method for synthesis of monosaccharides has been developed.

It involved reaction the formite salt with a precursor made up of one carbon atom and containing a carbonyl group.

Glycolaldehyde, glyceraldehyde, tetroses, pentoses, and hexoses were found to be the products of the stepwise addition of such a reagent to the corresponding substrates.

The formite ion adds across the double bond and gives rise to the alkoxide salt of the parent sugar.

On protonation this yields the respective monosaccharide. The next member of the homologous series is obtained by treating the resultant monosaccharide in a similar manner. Identification of the products so obtained was achieved by determination of molecular weights, melting points, Rf and infrared spectra, and number of hydroxyl groups.

The results obtained were found to be consistent with those cited in the literature.

Main Subjects

Chemistry

No. of Pages

221

Table of Contents

Table of contents.

Abstract.

Chapter One : Introduction.

Chapter Two : Experimental materials and methods.

Chapter Three : Results and discussion.

References.

American Psychological Association (APA)

Abd al-Rahman, Sittanah Ahmad al-Khatim. (2012). Synthesis of monosaccharides. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-364634

Modern Language Association (MLA)

Abd al-Rahman, Sittanah Ahmad al-Khatim. Synthesis of monosaccharides. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University. (2012).
https://search.emarefa.net/detail/BIM-364634

American Medical Association (AMA)

Abd al-Rahman, Sittanah Ahmad al-Khatim. (2012). Synthesis of monosaccharides. (Doctoral dissertations Theses and Dissertations Master). Omdurman Islamic University, Sudan
https://search.emarefa.net/detail/BIM-364634

Language

English

Data Type

Arab Theses

Record ID

BIM-364634