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The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury : a review
Joint Authors
Raghib, Ahmad
Atiyyah, Ahmad
Shihab Al-Din, Walid
al-Barbari, Fawzi
Gazarin, Sana
Shukr, Ahmad I.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 20, Issue 5 (31 Oct. 2009), pp.741-752, 12 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2009-10-31
Country of Publication
Saudi Arabia
No. of Pages
12
Main Subjects
Topics
Abstract EN
Thymoquinone (TQ), 2-Isopropyl-5-methyl-1, 4-benzoquinone, is one of the most active ingredients of Nigella Sativa seeds.
TQ has a variety of beneficial properties including antioxidative and anti-inflammatory activities.
Studies have provided original observations on the role of oxidative stress and inflammation in the development of renal diseases such as glomerulonephritis and drug-induced nephrotoxicity.
The renoprotective effects of TQ have been demonstrated in animal models.
Also, TQ has been used successfully in treating allergic diseases in humans.
The aim of this review is to highlight the importance of reactive oxygen species in renal pathophysiology and the intriguing possibility for a role of TQ in the prevention of and/or protection from renal injury in humans.
American Psychological Association (APA)
Raghib, Ahmad& Atiyyah, Ahmad& Shihab Al-Din, Walid& al-Barbari, Fawzi& Gazarin, Sana& Shukr, Ahmad I.. 2009. The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury : a review. Saudi Journal of Kidney Diseases and Transplantation،Vol. 20, no. 5, pp.741-752.
https://search.emarefa.net/detail/BIM-37381
Modern Language Association (MLA)
Raghib, Ahmad…[et al.]. The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury : a review. Saudi Journal of Kidney Diseases and Transplantation Vol. 20, no. 5 (Oct. 2009), pp.741-752.
https://search.emarefa.net/detail/BIM-37381
American Medical Association (AMA)
Raghib, Ahmad& Atiyyah, Ahmad& Shihab Al-Din, Walid& al-Barbari, Fawzi& Gazarin, Sana& Shukr, Ahmad I.. The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury : a review. Saudi Journal of Kidney Diseases and Transplantation. 2009. Vol. 20, no. 5, pp.741-752.
https://search.emarefa.net/detail/BIM-37381
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 748-752.
Record ID
BIM-37381