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Glucose metabolism abnormalities among pediatric acute lymphoblastic leukemia survivors : assessment and relation to body mass index and waist to hip ratio
Joint Authors
Rajab, Siham M.
al-Rashidi, Faridah H.
Badr, Iman A.
Abd al-Rahim, Ahmad H.
Source
Egyptian Pediatric Association Gazette
Issue
Vol. 61, Issue 1 (31 Mar. 2013), pp.7-14, 8 p.
Publisher
Egyptian Pediatric Association
Publication Date
2013-03-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Topics
- Children
- Metabolism
- Leukemia
- Diabetes
- Human body
- Glucose
- Anthropometry
- Body mass index
- Acute lymphocytic leukemia
Abstract EN
-Background: As survival rates of pediatric acute lymphoblastic leukemia (ALL) improve, attention is turning to side and late effects of therapy including glucose metabolism abnormalities.
Objective: To asses the presence of abnormal glucose metabolism in pediatric ALL survivors and its possible relation to body mass index (BMI), waist to hip ratio and treatment related factors.
Subjects and methods: Retrospective study with a prospective follow-up of 12 ALL survivors who had been off chemotherapy for >9 months was done.
Fifteen healthy sex and age matched children were involved as controls.
Body mass index (BMI) waist to hip ratio (WHR), and Oral glucose tolerance test (OGTT) were performed with assessment of glycated hemoglobin (Hb A1C) and insulin sensitivity indices.
Results: At study time the mean BMI, WHR, all components of the OGTT (except the 2 h post load glucose), all indices of insulin sensitivity and the mean Hb A1C% were significantly higher compared to those of the controls.
Two survivors (16.6%) developed transient hyperglycemia
American Psychological Association (APA)
al-Rashidi, Faridah H.& Rajab, Siham M.& Badr, Iman A.& Abd al-Rahim, Ahmad H.. 2013. Glucose metabolism abnormalities among pediatric acute lymphoblastic leukemia survivors : assessment and relation to body mass index and waist to hip ratio. Egyptian Pediatric Association Gazette،Vol. 61, no. 1, pp.7-14.
https://search.emarefa.net/detail/BIM-374550
Modern Language Association (MLA)
al-Rashidi, Faridah H.…[et al.]. Glucose metabolism abnormalities among pediatric acute lymphoblastic leukemia survivors : assessment and relation to body mass index and waist to hip ratio. Egyptian Pediatric Association Gazette Vol. 61, no. 1 (2013), pp.7-14.
https://search.emarefa.net/detail/BIM-374550
American Medical Association (AMA)
al-Rashidi, Faridah H.& Rajab, Siham M.& Badr, Iman A.& Abd al-Rahim, Ahmad H.. Glucose metabolism abnormalities among pediatric acute lymphoblastic leukemia survivors : assessment and relation to body mass index and waist to hip ratio. Egyptian Pediatric Association Gazette. 2013. Vol. 61, no. 1, pp.7-14.
https://search.emarefa.net/detail/BIM-374550
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 13-14
Record ID
BIM-374550