Mutagenic activity of some platinum and ruthenium complexes with N-heterocyclic ligands in salmonella typhimurium TA 1530 and TA 98
Joint Authors
Zaghal, Makram H.
Sadiq, Mayy F.
Source
Mu'tah Journal for Research and Studies : Natural and Applied Sciences Series
Issue
Vol. 12, Issue 3 (30 Apr. 1997), pp.213-223, 11 p.
Publisher
Mutah University Deanship of Academic Research
Publication Date
1997-04-30
Country of Publication
Jordan
No. of Pages
11
Main Subjects
Abstract EN
The mutagenic activity of some platinum and ruthenium complexes with 2,2’-biquinoline (biq) and 2-(2,-pyridyl)qumolme (pq) was examined in strains of Salmonella typhimurium TA 1530 and TA 98.
The complexes cw-[Pt(NN)X2)] (NN=biq, X=C1; NN=pq, X=C1, Br), Pt3(biq)2I6 and mer-[Ru(biq)?Cl3]*2H20 exhibit significant mutagenic activity while m^r-[Ru(pq)Cl3(C2H5OH)], [Ru(pq)Cl4].
3H20 and [Ru(pq) (DMSO)2Cl2] .0.5H20 show much weaker mutagenic activity.
The platinum complexes appear to be more active via induction of frameshift than base substitution mutations while mer-[Ru(biq)2Cl3].2H00 is highly mutagenic via base substitution.
American Psychological Association (APA)
Zaghal, Makram H.& Sadiq, Mayy F.. 1997. Mutagenic activity of some platinum and ruthenium complexes with N-heterocyclic ligands in salmonella typhimurium TA 1530 and TA 98. Mu'tah Journal for Research and Studies : Natural and Applied Sciences Series،Vol. 12, no. 3, pp.213-223.
https://search.emarefa.net/detail/BIM-395142
Modern Language Association (MLA)
Zaghal, Makram H.& Sadiq, Mayy F.. Mutagenic activity of some platinum and ruthenium complexes with N-heterocyclic ligands in salmonella typhimurium TA 1530 and TA 98. Mu'tah Journal for Research and Studies : Natural and Applied Sciences Series Vol. 12, no. 3 (Apr. 1997), pp.213-223.
https://search.emarefa.net/detail/BIM-395142
American Medical Association (AMA)
Zaghal, Makram H.& Sadiq, Mayy F.. Mutagenic activity of some platinum and ruthenium complexes with N-heterocyclic ligands in salmonella typhimurium TA 1530 and TA 98. Mu'tah Journal for Research and Studies : Natural and Applied Sciences Series. 1997. Vol. 12, no. 3, pp.213-223.
https://search.emarefa.net/detail/BIM-395142
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 222-223
Record ID
BIM-395142
