Evaluation of antioxidant and antibacterial activity of methanolic extracts of Gentiana kurroo royle

Abstract EN

Abstract In this study our objective was to evaluate the antioxidant and antimicrobial activity of methanolic extracts of leaves and roots of Gentiana kurroo.

The antioxidant activities of the extracts were examined using different biochemical assays namely diphenylpicrylhydrazyl (DPPH), nitroblue tetrazolium (NBT) and ferric reducing power (FRAP).

In all the assays, root extract exhibited stronger antioxidant activity than that of leaves.

The antibacterial activity of the extracts was also evaluated and MIC values were calculated by broth dilution method.

Although, the extracts prevented the growth of both Gram positive and Gram negative bacteria, the MIC values of methanolic extract of the leaves were higher than those of the root extract.

The antibacterial and antioxidant activity of the extracts was found to be positively associated with the total phenolic and flavonoid content of the extracts.