Antioxidant and hepatoprotective activity of fruit extracts of Tetrapleura tetraptera (schum & thonn) taubert
Joint Authors
Okoli, Jane T. N.
Agbo, Matthias O.
Ukekwe, Ikechukwu F.
Source
Jordan Journal of Biological Sciences
Issue
Vol. 7, Issue 4 (31 Dec. 2014), pp.251-255, 5 p.
Publisher
The Hashemite University Deanship of Academic Research and Graduate
Publication Date
2014-12-31
Country of Publication
Jordan
No. of Pages
5
Main Subjects
Topics
Abstract EN
The antioxidant and hepatoprotective activity of Tetrapleura tetraptera extracts in carbon tetrachloride (CCl4)-induced liver injury in rats was investigated.
T.
tetraptera extracts showed varying levels of protective action against CCl4-induced liver damage as evidenced through the significant reduction in the activities of serum marker enzymes for liver damage (alanine transaminase, aspartate transaminase, and alkaline phosphatase), and bilirubin levels when compared with CCl4- intoxicated control rats.
The extracts decreased the elevation in the activities of the enzymes in the liver.
They also protected against CCl4 induced lipid peroxidation.
The extracts reduced CCl4-liver induced necrosis in dose dependent manner.
These results indicated that fruit extracts of T.
tetraptera possess a hepatoprotective property against CCl4- induced liver damage which was mediated through its antioxidative defenses.
American Psychological Association (APA)
Okoli, Jane T. N.& Agbo, Matthias O.& Ukekwe, Ikechukwu F.. 2014. Antioxidant and hepatoprotective activity of fruit extracts of Tetrapleura tetraptera (schum & thonn) taubert. Jordan Journal of Biological Sciences،Vol. 7, no. 4, pp.251-255.
https://search.emarefa.net/detail/BIM-428471
Modern Language Association (MLA)
Okoli, Jane T. N.…[et al.]. Antioxidant and hepatoprotective activity of fruit extracts of Tetrapleura tetraptera (schum & thonn) taubert. Jordan Journal of Biological Sciences Vol. 7, no. 4 (Dec. 2014), pp.251-255.
https://search.emarefa.net/detail/BIM-428471
American Medical Association (AMA)
Okoli, Jane T. N.& Agbo, Matthias O.& Ukekwe, Ikechukwu F.. Antioxidant and hepatoprotective activity of fruit extracts of Tetrapleura tetraptera (schum & thonn) taubert. Jordan Journal of Biological Sciences. 2014. Vol. 7, no. 4, pp.251-255.
https://search.emarefa.net/detail/BIM-428471
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 255
Record ID
BIM-428471